New · posted Nov 13
ICON · Pharmaceuticals
Senior Director, Clinical Operations
- Remote, US
- Remote
- Full-time
- Director
The role
Senior Director, Clinical Operations
At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.
As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.
As a Senior Director, Clinical Operations at ICON, you will provide strategic and operational leadership across clinical programs while building strong client partnerships and helping drive account growth. This highly visible, client-facing role is ideal for an experienced Clinical Operations Director ready to broaden their impact across global clients, new business opportunities and existing accounts.
What you need
Required qualifications and experience
- Bachelor’s degree in a life sciences, healthcare, or related field, or equivalent relevant experience.
- Advanced degree preferred but not required.
- Significant experience in Clinical Operations within a CRO, pharmaceutical, biotechnology or related clinical research environment.
- Current or recent experience operating at the Director level or equivalent.
- Demonstrated success managing senior client and stakeholder relationships.
- Strong influencing, communication, negotiation and problem-solving skills.
- Ability to operate effectively in a highly client-facing environment.
- Demonstrated ability to take ownership, work proactively and drive results.
- Ability to constructively challenge stakeholders and navigate complex situations.
- Experience working effectively within global and cross-functional teams.
- Flexibility to support global clients across different time zones.
Preferred qualifications and experiencenice to have
- Experience with RFPs and proposal development.
- Experience participating in or leading bid defenses.
- Client negotiation experience.
- Experience supporting business development, account expansion or new business opportunities.
- Demonstrated ability to influence clients and build relationships that support long-term partnerships and growth.
- Strong learning agility and willingness to develop new commercial and business development capabilities.
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
What you'll do
Your focus will be on leading clinical operations delivery, strengthening client relationships, influencing stakeholders and proactively identifying solutions and opportunities to grow our partnerships.
Key responsibilities include
- Provide strategic and operational leadership across assigned clinical programs and accounts.
- Build trusted relationships with clients and senior internal stakeholders.
- Proactively influence and educate clients on operational processes, solutions and best practices.
- Identify opportunities to strengthen client partnerships and support account growth.
- Lead with confidence, constructively challenging or pushing back on stakeholders when needed to drive the right outcomes.
- Support new and existing business opportunities, including RFPs, proposals, bid defenses and client negotiations.
- Partner across global teams to ensure effective delivery and alignment with client expectations.
- Anticipate challenges, identify solutions and take ownership of driving issues through resolution.
- Work flexibly across global accounts and time zones based on client and business needs.
Pay and benefits
ICON didn't publish pay for this role
See what similar roles pay on Regulatory Jobs, or try the salary calculator.
Rewards & Benefits
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Equal opportunity, accessibility and legal noticesICON's statements, word for word
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Job intelligence
The context around this role
Live data · November 13, 2026
Salary intelligence
How the pay compares
Director roles in the US43 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| All US (middle half) | $201,000 | $233,000 | $244,000 |
Comparisons: the base pay employers published on open Clinical Operations roles at the same level on Regulatory Jobs, November 13, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Operations
The general path across 104 open Clinical Operations roles on Regulatory Jobs, with the titles they carry most. Not ICON's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 32 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership11
- Lab testing and methods1
- Clinical trial conduct1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Operations work in pharmaceuticals, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trials
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
ICON on Regulatory Jobs
- 168
- Open roles
- 168
- Distinct roles
- 39
- Locations
By discipline
- Clinical162 92%
- Quality11 6%
- Regulatory4 2%
By level
- Associate & Specialist77 44%
- Senior & Principal70 40%
- Manager23 13%
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Senior Director, Clinical Operations at ICON
Open until filled.