New · posted Nov 5
ICON · Pharmaceuticals
Sr Site Director of Clinical Research (Phase I)
- Salt Lake City, UT
- On-site
- Full-time
- Director
The role
Sr Site Director of Clinical Research (Phase I)
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
We are currently seeking a Senior Director, Clinical Operations (Site Head) to join our diverse and dynamic Lenexa-based team. As the Site Head, you will play a pivotal role in overseeing the planning, execution, and management of Phase 1 clinical trials, ensuring operational excellence and adherence to regulatory standards. You will contribute to the success of our clinical programs by providing strategic leadership, optimizing operational processes, and ensuring the highest quality of trial execution.
What you need
- Advanced degree in a relevant field (e.g., Medicine, Life Sciences, Pharmacology)
- Extensive experience in Early Phase clinical research and development, with a proven track record of success in leading clinical trials
- Strong leadership and management skills, with the ability to inspire and motivate teams
- Excellent communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholders
- In-depth knowledge of regulatory requirements and guidelines governing clinical research
- Ability to travel up to 10%
- Ability to be in the Salt Lake City UT, location daily
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Skills named in this posting
- Early Phase clinical research
- Phase 1 clinical trial leadership
- Study start-up and clinical monitoring oversight
- Regulatory requirements for clinical research
- Budget and financial oversight
- Team leadership and line management
- Client and executive stakeholder communication
- Advanced degree in Medicine, Life Sciences or Pharmacology
What you'll do
What you will be doing
- Lead site-level strategy and execution at the Lenexa location, with accountability for resourcing, line management, training, quality, and operational delivery.
- Oversee and optimize all Study Start Up and Clinical Monitoring activities to ensure rapid activation, regulatory compliance, and strong performance metrics.
- Manage site-level budget and provide financial oversight for clinical and study start-up functions, driving both productivity and quality.
- Serve as the senior liaison with the VP of Global Clinical Operations for critical issues, client deliverables, and business development opportunities.
- Represent ICON at executive-level meetings, client steering committees, and bid defenses, promoting the site’s capabilities and contributing to growth strategy.
- Foster a culture of high performance, innovation, and continuous improvement aligned with ICON’s core values.
- Support business development and client relationship efforts, ensuring excellent customer satisfaction and regional market success.
Pay and benefits
ICON didn't publish pay for this role
See what similar roles pay on Regulatory Jobs, or try the salary calculator.
Rewards & Benefits
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Where you'll work
Salt Lake City, UTOn-siteOpen in Maps (opens in a new tab)
More jobs in Salt Lake City, UTEqual opportunity, accessibility and legal noticesICON's statements, word for word
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Job intelligence
The context around this role
Live data · November 5, 2026
Salary intelligence
How the pay compares
Director roles in the US39 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| All US (middle half) | $207,000 | $235,000 | $245,500 |
Comparisons: the base pay employers published on open Clinical Operations roles at the same level on Regulatory Jobs, November 5, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Operations
The general path across 103 open Clinical Operations roles on Regulatory Jobs, with the titles they carry most. Not ICON's own promotion track.
Career resources on Clinical Operations
Skills DNA
What this role leans on
How many of the posting's 19 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership6
- Clinical trial conduct5
- Quality systems and risk2
- GMP and compliance1
- Documentation and SOPs1
- Early Phase clinical research
- Phase 1 clinical trial leadership
- Study start-up and clinical monitoring oversight
- Regulatory requirements for clinical research
- Budget and financial oversight
- Team leadership and line management
- Client and executive stakeholder communication
- Advanced degree in Medicine, Life Sciences or Pharmacology
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Operations work in pharmaceuticals, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trials
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
ICON on Regulatory Jobs
- 140
- Open roles
- 65
- Distinct roles
- 32
- Locations
By discipline
- Clinical129 92%
- Quality7 5%
- Regulatory4 3%
By level
- Associate & Specialist59 42%
- Senior & Principal58 41%
- Manager18 13%
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Sr Site Director of Clinical Research (Phase I) at ICON
Open until filled.