New · posted Nov 4
Revolution Medicines · Biotechnology
Senior Director, Clinical Operations
- Redwood City, CA
- Hybrid
- Full-time
- Director
The role
This is a unique opportunity for the right individual who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in organizing and running clinical trials. As the Senior Director of Clinical Operations, you will be responsible for the operational design and structure of, and accountable for the execution of, Revolution Medicines early-stage clinical studies. Specifically, you will be responsible for:
The development, management, and execution of the Clinical Development Plan (CDP) for clinical programs which includes clinical trial timeline estimates, budgets, and resource requirements.
Oversight over the execution of clinical trials, including CRO selection and site selection.
Successful planning and deployment of Clinical Operations staff for project and non-project related tasks. Establish clear roles and responsibilities for team members and include opportunities to stretch skills and enable growth.
Line management responsibilities include hiring, performance management, career development and mentorship.
Participate in or lead team meetings and collaborate with other functional groups within the company (e.g., Clinical Development, DMPK, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals regulations and International Council for Harmonization (ICH)/ GCP guideline.
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
What you need
Required Skills, Experience and Education
BS/MS Degree in a scientific discipline with a minimum of 12 years of clinical operations experience in the pharmaceutical or biotech industry.
Minimum of 7 years project and line management experience.
Extensive experience in leading and managing global phase 1-3 clinical trials within designated timelines, resources, and budgets.
Experience in working with cooperative group studies and investigator sponsored trials, preferred.
A demonstrable record of strong leadership and teamwork.
Extensive experience in selection of CROs/ vendors and management of external resources
Must have a working knowledge of data management, data review and analysis, and drug safety, pharmacovigilance and other related functions as related to clinical trial conduct.
Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment.
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy environment.
Excellent written and verbal communication skills.
Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.
Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.
Preferred Skillsnice to have
- Experience in oncology clinical trials.
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Base Pay Salary Range
$244,000—$305,000 USD
Skills named in this posting
Pay and benefits
$244,000 – $305,000 a year
Employer providedCompetitive cash compensation
Equity awards
Strong benefits
Learning and development opportunities
Where you'll work
Redwood City, CAHybridOpen in Maps (opens in a new tab)
More jobs in Redwood City, CAEqual opportunity, accessibility and legal noticesRevolution Medicines's statements, word for word
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Job intelligence
The context around this role
Live data · November 4, 2026
Salary intelligence
How the pay compares
This role's midpoint is 17% above the US median for Clinical Operations roles at this level.
This roleEmployer provided
Director roles in California11 roles publishing pay
Director roles in the US40 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $244,000 | — | $305,000 |
| California (middle half) | $241,000 | $244,000 | $290,250 |
| All US (middle half) | $209,000 | $235,250 | $248,500 |
This role: Revolution Medicines's own published range. Comparisons: the base pay employers published on open Clinical Operations roles at the same level on Regulatory Jobs, November 4, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Operations
The general path across 104 open Clinical Operations roles on Regulatory Jobs, with the titles they carry most. Not Revolution Medicines's own promotion track.
Career resources on Clinical Operations
Skills DNA
What this role leans on
How many of the posting's 26 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct10
- Collaboration and leadership10
- GMP and compliance2
- Documentation and SOPs2
- Investigations and CAPA1
- Data and digital systems1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Operations work in biotechnology, led by the one this posting names, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trialsNamed in the posting
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
Revolution Medicines on Regulatory Jobs
- 43
- Open roles
- 35
- Distinct roles
- 3
- Locations
By discipline
- Clinical27 63%
- Regulatory8 19%
- Quality7 16%
By level
- Director29 67%
- Manager10 23%
- Senior & Principal4 9%
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Senior Director, Clinical Operations at Revolution Medicines
Open until filled. $244K–$305K a year, employer provided.