New · posted Nov 1
Sarepta Therapeutics · Biotechnology
Associate Director, Clinical Operations Program Lead, Study Start-up & Feasibility
- Cambridge, MA
- Hybrid
- Full-time
- Director
The role
The Importance of the Role
We are seeking an associate director-level candidate with clinical operations experience, with specific expertise in feasibility and study start-up, who is interested in applying their experience to develop, build out, and implement innovative feasibility and study start-up activities within Sarepta that positively impacts our clinical programs.
The Associate Director, Clinical Operations Program Lead, Study Start-up and Feasibility will report to the Director, Patient Recruitment and Start-Up Strategy and lead a team to drive the strategy and implementation of country and site feasibility for our studies and support the internalization of country and site feasibility. Additionally, the candidate will work with early research and other stakeholders to build out the oversight model for Feasibility & Study Start-up. The candidate will drive the study start-up activities and be responsible for oversight of timelines and goals with respect to our clinical studies. The candidate will be responsible for 1) directing and overseeing the success of Sarepta’s clinical trial feasibility process, 2) leading the development of feasibility and start-up strategies including study-specific plans, 3) directing and overseeing the success of the Sarepta’s clinical trial start-up activities, 4) and working with both internal and external vendors.
This is a highly cross-functional position, collaborating with internal teams, CROs, and vendors. The candidate must be comfortable working directly with clinical trial sites.
The contribution of the candidate directly supports the goals of the Development Operations organization under R&D.
This is a great opportunity for an individual with an operational background and innovative mindset to help us accelerate study execution to support Sarepta’s goal of Patient’s First.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
What you need
Desired Education and Skillsnice to have
- BA / BS degree in a related field; 10+ years related experience in the pharmaceutical or biotech industry within a clinical operations or project management role or similar
- Experience in clinical study budget planning, and program implementation
- Experience with both direct line management and dotted line reporting
- Experience in developing feasibility questionnaires
- Experience with protocol and ICF development and review
- Experience in clinical study start-up
- Experience with rare disease / difficult to recruit populations a plus
- Experience identifying and managing multiple CROs, vendors, budgets, KPIs.
- Comprehensive regulatory knowledge, including ICH and GCPs
- Exceptional organizational skills and ability to deal with competing priorities
- Strong analytical reasoning and problem-solving ability
- Excellent PowerPoint slide development and presentation skills
- Ability to multi-task, work independently and as part of a multidisciplinary team, exercise sound judgement and escalate issues when necessary
What you'll do
Primary Responsibilities Include
- Develop and implement the feasibility and start-up strategies to support the success of Sarepta clinical studies.
- Gather cross-functional, country-level input to inform robust feasibility strategies.
- Develop and manage integrated feasibility and site start-up timelines, and report on progress, including plans to address potential timing risks or gaps.
- Establish study specific meeting series to review clinical trial feasibility data and start-up activities with study leads, MSLs, and the CRO. The candidate will report metrics to larger teams including senior management.
- Lead calls with Sarepta and the CRO to manage feasibility and study start-up activities and ensure the study timelines are achieved.
- Oversee study feasibility activities including country, site, and investigator selection for participation in Sarepta-lead studies.
- Foster a culture of innovation by developing new ideas and programs to advance feasibility and support departmental growth.
- Provide guidance and mentoring to junior members of the Study Start-up and Feasibility Team.
- Create reporting tools to measure ongoing activities and other key performance, quality, and effectiveness indicators.
- Partner with Clinical Operations and CRO teams, and other key stakeholders to implement innovative feasibility efforts including collection of data within CTMS.
- Support and or lead the development of Charters or SOPs as it relates to Study Start-up and Feasibility.
- May have direct reports.
Pay and benefits
$161,000 – $201,000 a year
Employer providedWhat Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
Physical and emotional wellness support
Financial wellness support
Support for caregivers
Competitive compensation and benefit package
Where you'll work
Cambridge, MAHybridOpen in Maps (opens in a new tab)
More jobs in Cambridge, MA
From the posting
About Sarepta Therapeutics
Why Sarepta? Why Now?
Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne Muscular Dystrophy and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our next-generation siRNA platform is focused on chronically administered therapies for neurodegenerative and pulmonary diseases.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
Equal opportunity, accessibility and legal noticesSarepta Therapeutics's statements, word for word
position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time.The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 22% below the US median for Clinical Operations roles at this level.
This roleEmployer provided
Director roles in Massachusetts6 roles publishing pay
Director roles in the US35 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $161,000 | — | $201,000 |
| Massachusetts (middle half) | $198,875 | $200,000 | $214,250 |
| All US (middle half) | $202,500 | $233,000 | $243,000 |
This role: Sarepta Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Operations roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Operations
The general path across 93 open Clinical Operations roles on Regulatory Jobs, with the titles they carry most. Not Sarepta Therapeutics's own promotion track.
Career resources on Clinical Operations
Skills DNA
What this role leans on
How many of the posting's 35 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct11
- Collaboration and leadership10
- Documentation and SOPs5
- Lab testing and methods1
- Investigations and CAPA1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
Sarepta Therapeutics on Regulatory Jobs
- 8
- Open roles
- 8
- Distinct roles
- 4
- Locations
By discipline
- Quality3 38%
- Clinical3 38%
- Regulatory2 25%
By level
- Director5 63%
- Manager3 38%
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Associate Director, Clinical Operations Program Lead, Study Start-up & Feasibility at Sarepta Therapeutics
Open until filled. $161K–$201K a year, employer provided.