New · posted Oct 31
Kymera Therapeutics · Biotechnology
Senior Clinical Trial Manager
- Watertown, MA
- On-site
- Full-time
- Manager
The role
How we work
- PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
- COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
- BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.
What you need
Skills and experience you’ll bring
- Bachelor of Science in Life Sciences and 7+ years as a project/clinical trial manager in biotech/pharmaceutical industry.
- Experience working on large, global, complex Phase 2/3 clinical trial(s).
- Broad knowledge of regulatory and ICH GCP guidelines, HIPAA, Protection of Human Research Subjects.
- Strong project management skills with the ability to manage multiple trials simultaneously.
- Excellent problem-solving, leadership, and communication skills.
- Ability to work in a fast-paced, dynamic environment with cross-functional teams.
What you'll do
How you’ll make an impact
- Contribute to the planning, implementation and execution of a global clinical trial
- Responsible for management of vendors to support clinical trial execution
- Plan, execute, and lead study-specific meetings (e.g., internal core team meetings, investigator meetings, etc), as needed
- Provide input for the design of the Informed Consent Form(s), eCRFs, monitoring conventions, edit checks, etc.
- Provide study-specific training and leadership to clinical research staff, CRO, CRAs, sites and other contract personnel.
- Manage study timelines and metrics to ensure completion of study deliverables
- Support site selection, qualification, initiation, and monitoring activities.
- Review monitoring reports to ensure quality and resolution of site-related issues.
- Ensure timely enrollment and data collection at clinical trial sites.
- Collaborate with the data management team to ensure data integrity and timely database lock.
- Review and analyze clinical trial data to identify trends and potential issues.
- Ensure tracking and review of protocol deviations and assess impact on study data
- Develop relationships with investigators and site staff
- Work closely with CRO and Medical Monitor to ensure safety and efficacy data appropriately summarized to facilitate review.
- Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
- Maintain accurate and complete trial documentation.
- Proactively identify and resolve clinical project issues
Pay and benefits
$145,000 – $215,000 a year
Employer provided- Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
- The anticipated base salary range for this role is $145,000 – $215,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
- Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.
Annual bonus
Equity participation
Comprehensive benefits
Where you'll work
Watertown, MAOn-siteOpen in Maps (opens in a new tab)
More jobs in Watertown, MA
From the posting
About Kymera Therapeutics
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
Equal opportunity, accessibility and legal noticesKymera Therapeutics's statements, word for word
Equal Employment Opportunity
Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 11% above the US median for Clinical Trial Management roles at this level.
This roleEmployer provided
Manager roles in Massachusetts6 roles publishing pay
Manager roles in the US26 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $145,000 | — | $215,000 |
| Massachusetts (middle half) | $155,500 | $175,000 | $176,500 |
| All US (middle half) | $150,000 | $162,000 | $175,000 |
This role: Kymera Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Trial Management roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Trial Management
The general path across 33 open Clinical Trial Management roles on Regulatory Jobs, with the titles they carry most. Not Kymera Therapeutics's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 26 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct14
- Collaboration and leadership7
- Investigations and CAPA3
- Documentation and SOPs2
- GMP and compliance1
- Lab testing and methods1
- Validation and qualification1
- Data and digital systems1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
- FDAFDA data integrity guidance(official source, opens in a new tab)Data Integrity and Compliance With Drug CGMP: Questions and Answers
- ICHICH quality guidelines(official source, opens in a new tab)Q1 stability, Q2(R2) analytical validation, Q7, Q9 risk management, Q10 quality systems
- ICHICH E6 good clinical practice(official source, opens in a new tab)The international standard for the conduct of clinical trials
Company hiring pulse
Kymera Therapeutics on Regulatory Jobs
- 7
- Open roles
- 7
- Distinct roles
- 1
- Locations
By discipline
- Clinical5 71%
- Regulatory2 29%
By level
- Director4 57%
- Manager2 29%
- Senior & Principal1 14%
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Senior Clinical Trial Manager at Kymera Therapeutics
Open until filled. $145K–$215K a year, employer provided.