New · posted Oct 31
BridgeBio · Biotechnology
Principal Clinical Database Systems Programmer
- Remote, US
- Remote
- Full-time
- Senior & Principal
The role
Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
Where You'll Work
This is a U.S.-based remote role that will require quarterly, or as needed visits to our San Francisco Office. There is <10% travel anticipated for conference attendance, Biometrics/DM meetings, BBIO organization event attendance.
What you need
· Bachelor’s degree (or equivalent) in Science and/or Computer Systems/IT background
· Minimum 5-7 year experience in a pharmaceutical/biotech setting
· Advanced technical expertise in databases, EDC platforms (e.g. Medidata Rave, Veeva), data imports/integrations and data visualization tools (e.g. Tableau, Spotfire) and Python programming language is a plus
· Advanced programming and analytical skills using SQL, BASE/SAS, SAS/STAT, SAS MACROS
· Ability to work independently to create standard datasets, program edit checks and produce quality data review outputs
· Demonstrated understanding of CDISC and SDTM requirements and implementation guidelines, able to create and validate CDISC standard datasets
· Knowledge of ICH GCP and Good Clinical Data Management guidelines
· <10% Travel to BridgeBio Headquarters or Biometrics/DM meetings, as required
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
Salary
$172,000—$188,600 USD
As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
Skill Development & Career Paths
- People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
- We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
- We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities
What you'll do
The Principal Clinical Database Systems Programmer will be responsible for performing SAS or SQL data programming to execute the design, build, and maintenance of clinical data collection systems. This includes developing customized, programmed data listings and data reports/visualizations, and/or EDC study database builds. The Principal Clinical Programmer will manage the study-defined specifications and requirements to lead clinical programming activities across one or more studies for the DM Operations and Clinical Development functional areas and liaise with our biostatisticians to understand final requirements and structure of study data/database design being presented.
· Creates standard and/or custom programs/reports using data analytics tools such as SAS, Tableau, or other data visualization tools to support data oversight and review by data managers or other data reviewers.
· Leads EDC database build programming, testing, and migration of CRFs and edit checks or dynamics (database specifications, etc.) using EDC platforms (e.g. Veeva Vault, Medidata Rave).
· Collaborates with clients, peers, programmers, project teams, and/or requestors to clarify and finalize data specifications; uses expanded technical skills to meet evolving project needs.
· Supports the development, delivery and maintenance of clinical data review standards, tools and systems, across various data sources (e.g., clinical data, safety and operational data).
· Supports initiatives for Data Management and Clinical Programming for clinical data review bridging and database development activities, meetings, discussions.
· Assists in the management of electronic data from external data sources/vendors in partnership with the Data Management Lead for import or integration to clinical database tools. Liaises with vendors as needed to facilitate electronic data transfers and/or data specification requirements.
· Assists in review and approval of required study documentation, including design specifications, user requirements, data transfer specifications and data standards.
· Provides leadership, training, guidance, and support to other department members on data review tools and clinical database development.
Pay and benefits
$172,000 – $188,600 a year
Employer providedFinancial & Rewards
Market-leading compensation
401(k) with employer match
Employee Stock Purchase Program (ESPP)
Pre-tax commuter benefits (transit and parking)
Referral bonus for hired candidates
Subsidized lunch and parking on in-office days
100%
100% employer-paid medical, dental, and vision premiums for you and your dependents
Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
Fertility & family-forming benefits
Expanded mental health support (therapy and coaching resources)
Hybrid work model with flexibility
Flexible, “take-what-you-need” paid time off and company-paid holidays
Comprehensive paid medical and parental leave to care for yourself and your family
Equal opportunity, accessibility and legal noticesBridgeBio's statements, word for word
By applying, you acknowledge that BridgeBio will process your personal information as described in our Global Candidate Privacy Notice.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 22% above the US median for Clinical Data Management roles at this level.
This roleEmployer provided
Senior & Principal roles in the US7 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $172,000 | — | $188,600 |
| All US (middle half) | $132,500 | $148,000 | $159,500 |
This role: BridgeBio's own published range. Comparisons: the base pay employers published on open Clinical Data Management roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Data Management
The general path across 29 open Clinical Data Management roles on Regulatory Jobs, with the titles they carry most. Not BridgeBio's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 26 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership11
- Data and digital systems8
- Documentation and SOPs7
- Clinical trial conduct4
- Lab testing and methods2
- GMP and compliance1
- Validation and qualification1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
BridgeBio on Regulatory Jobs
- 4
- Open roles
- 4
- Distinct roles
- 1
- Locations
By discipline
- Clinical3 75%
- Regulatory1 25%
By level
- Director2 50%
- Senior & Principal2 50%
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Principal Clinical Database Systems Programmer at BridgeBio
Open until filled. $172K–$189K a year, employer provided.