New · posted Nov 1
Biogen · Biotechnology
Principal, Clinical Data Lead
- Cambridge, MA +1 more
- Hybrid
- Full-time
- Senior & Principal
The role
Preference will be given to candidates who can work in a hybrid arrangement, with weekly presence onsite at our offices in Cambridge, MA or in Durham, NC. However, remote work may be available for highly qualified candidates residing within the United States.
About this role
The Principal Clinical Data Lead provides leadership and expertise in all aspects of Clinical Data Management for assigned clinical trials. Manage the flow of clinical data throughout the study lifecycle, from initial eCRF development through clinical study reporting. This role serves as the accountable Data Management representative on study teams, ensuring high-quality data deliverables, effective planning, risk management, vendor oversight, inspection readiness, and successful study execution. The position may support program-level responsibilities, special initiatives, quality oversight, process improvement, and mentoring of Clinical Data Managers.
What you need
Required skills
- Bachelor's degree in a scientific or quantitative discipline preferred.
- 5-7 years of clinical data management experience with accountability across study start-up, conduct, and database lock.
- Robust experience with EDC platforms such as Medidata Rave and data review tools including eCS elluminate.
- Deep understanding of drug development and the biopharmaceutical industry.
- Strong project management skills with the ability to lead cross-functional teams; project management certification preferred.
- Exceptional attention to detail and ability to manage multiple competing priorities.
- Experience building and maintaining effective external stakeholder and vendor relationships.
- Deep knowledge of data management outsourcing models, including FSP and CRO partnerships.
- Demonstrated ability to influence without formal authority.
- Excellent written and verbal communication skills.
A passionate and experienced clinical data leader with exceptional planning, communication, and leadership skills. You bring deep expertise in clinical data management systems, maintain a strong focus on quality and detail, and take accountability for the successful delivery of all CDM outputs.
Preferred skillsnice to have
- Project Management certification.
Base salary varies depending on location.
Job Level: Management
What you'll do
- Lead end-to-end clinical data management activities across assigned studies and programs.
- Serve as the single point of contact for execution of data management deliverables on assigned studies and programs.
- Ensure consistent application of DM standards and quality across assigned trials.
- Develop and oversee risk mitigation and action plans.
- Monitor study metrics, identify trends, and escalate risks as appropriate.
- Partner with internal and external stakeholders including Biometrics, Clinical, Medical, Safety, Regulatory, CROs, and FSP partners.
- Perform holistic review of study data using data review and analytics tools.
- Drive process improvement, innovation, and operational excellence initiatives.
- Manage vendor performance and quality issues and support audit and inspection readiness.
- Support special projects and cross-functional initiatives.
Pay and benefits
$122,000 – $163,250 a year
Employer providedAdditional Information
The base compensation range for this role is: $122,000.00-$163,250.00
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Medical, dental, vision and life insurance
401(k) with company match
Employee stock purchase plan
Paid vacation, holidays and sick time
Paid maternity and parental leave
Tuition reimbursement up to $10,000
Where you'll work
Cambridge, MA +1 moreHybridOpen in Maps (opens in a new tab)
Also posted for: Durham, NC
More jobs in Cambridge, MA +1 more
From the posting
About Biogen
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.
Equal opportunity, accessibility and legal noticesBiogen's statements, word for word
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 3% above the US median for Clinical Data Management roles at this level.
This roleEmployer provided
Senior & Principal roles in the US14 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $122,000 | — | $163,250 |
| All US (middle half) | $127,375 | $138,750 | $150,625 |
This role: Biogen's own published range. Comparisons: the base pay employers published on open Clinical Data Management roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Data Management
The general path across 54 open Clinical Data Management roles on Regulatory Jobs, with the titles they carry most. Not Biogen's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 26 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership8
- Data and digital systems6
- Clinical trial conduct4
- GMP and compliance2
- Documentation and SOPs2
- Quality systems and risk2
Company hiring pulse
Biogen on Regulatory Jobs
- 23
- Open roles
- 23
- Distinct roles
- 4
- Locations
By discipline
- Clinical12 52%
- Quality7 30%
- Regulatory4 17%
By level
- Director7 30%
- Senior & Principal7 30%
- VP & Executive4 17%
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Principal, Clinical Data Lead at Biogen
Open until filled. $122K–$163K a year, employer provided.