New · posted Oct 31
Corcept Therapeutics · Pharmaceuticals
Lead Medical Safety Physician
- Redwood City, CA
- On-site
- Full-time
- Director
The role
For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases.
Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today.
Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com.
Reporting to the Vice President, Head of Patient Safety & Pharmacovigilance, this role will be responsible for leading the Medical Safety Physician function, ensuring the quality, consistency, and medical integrity of safety assessments across the portfolio. The individual will provide oversight of medical review, signal evaluation, and benefit–risk assessments across clinical development and post-marketing programs.
- Operate as a peer functional leader alongside the Head of Safety Science, Head of Safety Operations, and QPPV(s) within the Patient Safety & Pharmacovigilance organization, partnering to provide strategic leadership, ensure effective governance, and maintain an integrated approach to patient safety and pharmacovigilance across the portfolio
- Partner with key internal stakeholders, including Clinical Development and Medical Affairs to ensure alignment of safety insights across the product lifecycle while maintaining independent medical judgment on safety and benefit–risk decisions
What you need
Preferred Education and Experiencenice to have
- Strategic medical leadership and executive presence
- Clinical judgment and benefit–risk decision-making
- Medical governance and patient safety leadership
- Cross-functional influence and stakeholder management
- Organizational leadership, talent development, and succession planning
- Regulatory/ health authority engagement
- Executive communication and presentation skills
- Driving organizational change and continuous improvement
Applicants must be currently authorized to work in the United States on a full-time basis.
Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs.
Preferred Skills, Qualifications and Technical Proficienciesnice to have
- MD required; board certification in a relevant specialty strongly preferred
- 12+ years of progressive leadership experience in the pharmaceutical or biotechnology industry, including significant experience in Medical Safety and pharmacovigilance; oncology experience required
- Demonstrated success leading Medical Safety organizations and managing teams of Medical Safety Physicians
- Deep expertise in safety signal management, medical review, aggregate safety assessment, and benefit–risk evaluation across clinical development and post-marketing products
- Extensive experience interacting with global health authorities and leading safety-related regulatory activities
- Strong understanding of global pharmacovigilance regulations and industry best practices
- Proven ability to influence cross-functional and executive-level decision-making and build effective partnerships across Patient Safety/Pharmacovigilance, Clinical Development, Regulatory Affairs, Medical Affairs and Biometrics
- Experience building, scaling, or leading Medical Safety functions in fast-paced or growing organizations preferred
What you'll do
Medical Safety Leadership
- Define and drive the medical safety strategy across the portfolio
- Provide senior medical safety leadership for safety interpretation and benefit–risk assessment
- Ensure consistent medical oversight of clinical and post-marketing safety activities
Team Leadership
- Lead, build, and develop a team of Medical Safety Physicians
- Set standards for medical review quality and consistency
- Scale the organization to support portfolio and geographic growth
Safety Review & Surveillance
- Lead medical evaluation of safety signals in partnership with Safety Science
- Ensure robust benefit–risk assessment across programs
- Integrate clinical interpretation into safety surveillance outputs
Key Collaboration
- Partner with Clinical Development to integrate safety into development strategy
- Partner with Medical Affairs to ensure consistent safety messaging
- Provide medical interpretation and benefit–risk input to cross-functional decisions
Regulatory & Governance
- Oversee medical input into DSURs, PADERs, and regulatory safety submissions
- Support health authority interactions and safety queries
- Contribute to cross-functional safety governance forums, providing medical expertise and benefit–risk input in cross-functional safety governance forums
Risk Management
- Identify and escalate safety risks at product and portfolio level
- Define medical risk mitigation strategies with cross-functional partners
- Drive continuous improvement in medical safety processes and standards
Pay
$298,000 – $350,600 a year
Employer providedThe pay range that the Company reasonably expects to pay for this headquarters-based position is $298,000 – $350,600; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education.
Where you'll work
Redwood City, CAOn-siteOpen in Maps (opens in a new tab)
More jobs in Redwood City, CAEqual opportunity, accessibility and legal noticesCorcept Therapeutics's statements, word for word
Corcept is an Equal Opportunity Employer
Corcept will not conduct interviews via text message or messaging platforms and will not ask you to download anything as part of your interview. Though we use third-party tools to help with advertising our jobs, please be vigilant in checking that the communication is in fact coming from Corcept.
For information on how Corcept collects, uses, discloses, protects, and otherwise processes personal information and an explanation of the rights and choices available to you with respect to your personal information, please refer to our Privacy Notice link.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 25% above the US median for Clinical Safety & Pharmacovigilance roles at this level.
This roleEmployer provided
Director roles in California18 roles publishing pay
Director roles in the US69 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $298,000 | — | $350,600 |
| California (middle half) | $227,125 | $254,250 | $280,750 |
| All US (middle half) | $213,500 | $260,000 | $281,000 |
This role: Corcept Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Safety & Pharmacovigilance roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Safety & Pharmacovigilance
The general path across 113 open Clinical Safety & Pharmacovigilance roles on Regulatory Jobs, with the titles they carry most. Not Corcept Therapeutics's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 48 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership20
- Quality systems and risk6
- Clinical trial conduct6
- Regulatory submissions4
- GMP and compliance1
Company hiring pulse
Corcept Therapeutics on Regulatory Jobs
- 22
- Open roles
- 22
- Distinct roles
- 1
- Locations
By discipline
- Clinical17 77%
- Regulatory3 14%
- Quality2 9%
By level
- Director10 45%
- Senior & Principal5 23%
- Manager4 18%
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Lead Medical Safety Physician at Corcept Therapeutics
Open until filled. $298K–$351K a year, employer provided.