New · posted Oct 31
Revolution Medicines · Biotechnology
Global Development Lead (GDL), Clinical Development
- Redwood City, CA
- Hybrid
- Full-time
- Director
The role
We are seeking an experienced oncology drug-development leader to serve as Global Development Lead (GDL) for one of Revolution Medicines’ most advanced clinical programs. This is a senior, program-accountable leadership role with end-to-end ownership of clinical development strategy and execution for a late-stage asset, including pivotal studies, regulatory engagement, and long-range planning.
The GDL functions as the single point of clinical accountability for the assigned program, setting direction, driving alignment across functions, and representing the program at internal governance bodies and externally with investigators, key opinion leaders, and global health authorities. This position sits at the Executive Director level within Clinical Development and carries program-level accountability and authority typically associated with the most senior clinical leaders in the organization.
In addition to program ownership, the GDL serves as a senior clinical advisor to development leadership, contributing perspective to cross-program and enterprise-level development discussions as appropriate.
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
Clinical Development Leadership
Depth of experience typically gained at least 13 years in oncology clinical development, or a combination of senior academic clinical leadership and relevant industry roles.
(Academic leadership may be counted when directly related to oncology trials and patient care.)
Demonstrated leadership of global, late-stage development programs, including design and execution of pivotal Phase 2/3 studies.
Experience owning or leading global regulatory strategy, including direct involvement in multiple interactions with global health authorities.
Experience contributing to or leading regulatory submissions (NDA/BLA/MAA); multiple submissions strongly preferred.
Enterprise Leadership & Influence
Proven ability to align and influence senior stakeholders across a highly matrixed organization.
Exceptional ability to communicate complex scientific and clinical concepts clearly to executives, cross-functional partners, and external experts.
Demonstrated skill in navigating conflict, establishing role clarity, and building durable cross-functional trust.
Demonstrated commitment to developing people and building strong, resilient teams.
Other
Excellent written and verbal communication skills.
Ability to travel approximately 25–30% (domestic and international).
San Francisco Bay Area preferred, but hybrid acceptable.
What you need
Medical & Scientific Qualifications
MD (or international equivalent) with board certification in Medical Oncology or Hematology/Oncology; adult solid tumor focus strongly preferred.
Recognized expertise in NSCLC developed through academic clinical leadership and/or substantial industry experience.
Preferred Skillsnice to have
Prior academic appointment in medical oncology with leadership of clinical trials.
Experience integrating translational and biomarker strategies into late-stage clinical development.
Publication record supporting disease-area credibility.
Experience supporting commercialization planning or launch readiness.
Exposure to cross-program or portfolio-level development strategy and governance.
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Base Pay Salary Range
$369,000—$424,000 USD
Skills named in this posting
- MD with board certification in Medical Oncology or Hematology/Oncology
- 13+ years oncology clinical development
- Pivotal Phase 2/3 study design and execution
- Global regulatory strategy and health authority interactions
- NDA/BLA/MAA submissions
- Cross-functional matrix leadership
- People leadership
- Translational and biomarker strategy
What you'll do
Program & Clinical Strategy
Own and lead the global clinical development strategy for the assigned program, integrating scientific, clinical, regulatory, biomarker, and commercial considerations.
Partner closely with the Project Team Leader (PTL) or Lifecycle Team Leader (LCL) to ensure that clinical development strategy, positions and decision-making are fully represented and integrated within lifecycle planning and decision-making for the molecule, with clear alignment on roles, decision rights and accountability.
Develop and maintain the Target Product Profile (TPP), Clinical Development Plan (CDP), risk assessments, scenario analyses, and long-range program roadmap.
Present strategic recommendations to internal governance bodies (e.g., DRG, SMT, PRG, ePRG) and drive high-quality, timely program decision-making.
Ensure strategy reflects deep disease-area insight, emerging science, competitive intelligence, and evolving regulatory expectations.
Execution & Oversight
Accountable for the design, execution, and delivery of pivotal and registration-enabling studies (Phase 2/3), including protocol strategy, enrollment and geographic planning, patient safety oversight, and data interpretation.
Ensure alignment and harmonization across related studies within the program and across regions to support coherent regulatory and lifecycle objectives.
Provide senior clinical leadership across functions to anticipate risk, resolve complex issues, and ensure delivery of critical milestones, leveraging matrixed teams rather than direct operational control.
Guide preparation of regulatory briefing materials and serve as the senior clinical representative in global health authority interactions.
Scientific & Medical Leadership
Serve as the program’s senior medical authority, providing deep expertise in pancreatic and colorectal cancers.
Translate scientific, translational, and biomarker insights into actionable clinical strategy.
Engage key opinion leaders, investigators, advisory boards, and external experts to refine development strategy and strengthen scientific and clinical positioning.
Cross-Functional & Enterprise Leadership
Serve as the clinical and strategic leader for the assigned program, with clear accountability for clinical direction and integrated decision-making across functions.
Lead a high-performing, cross-functional Global Development Team, in close partnership with the PTL or LCL, ensuring clarity of direction, strong collaboration, and accountability for outcomes.
Demonstrate the ability to lead through both influence and authority in situations where program priorities cut across functions, senior leaders, and organizational boundaries.
Partner with Medical Affairs and Commercial colleagues to ensure alignment between clinical strategy and future market needs.
Act as a visible senior leader within Clinical Development, modeling enterprise mindset and contributing to broader discussions on development strategy, standards, and best practices beyond the assigned program.
People Leadership & Organizational Impact
Assume leadership of an established, multidisciplinary Clinical Development Team, including multiple senior direct reports, with immediate accountability for alignment, performance, and delivery across the program.
Rapidly assess team capabilities, clarify roles and decision rights, and establish operating cadence to ensure seamless execution during critical late-stage development phases.
Demonstrated ability to step into complex, high-visibility leadership situations and effectively lead teams through transition, inflection points, or accelerated timelines.
Mentor senior clinical development staff and contribute to capability-building across the broader organization.
Model Revolution Medicines’ values of scientific rigor, transparency, inclusiveness, and commitment to patients.
Contribute to the evolution of development processes, tools, and governance practices that enhance efficiency, quality, and scalability across the portfolio.
Pay and benefits
$369,000 – $424,000 a year
Employer providedCompetitive cash compensation
Equity awards
Strong benefits
Learning and development opportunities
Where you'll work
Redwood City, CAHybridOpen in Maps (opens in a new tab)
More jobs in Redwood City, CAEqual opportunity, accessibility and legal noticesRevolution Medicines's statements, word for word
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 33% above the US median for Clinical Development roles at this level.
This roleEmployer provided
Director roles in California21 roles publishing pay
Director roles in the US93 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $369,000 | — | $424,000 |
| California (middle half) | $244,000 | $295,000 | $339,000 |
| All US (middle half) | $258,000 | $298,000 | $318,500 |
This role: Revolution Medicines's own published range. Comparisons: the base pay employers published on open Clinical Development roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Development
The general path across 116 open Clinical Development roles on Regulatory Jobs, with the titles they carry most. Not Revolution Medicines's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 51 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership24
- Clinical trial conduct13
- Regulatory submissions4
- Documentation and SOPs2
- Investigations and CAPA2
- Quality systems and risk1
- MD with board certification in Medical Oncology or Hematology/Oncology
- 13+ years oncology clinical development
- Pivotal Phase 2/3 study design and execution
- Global regulatory strategy and health authority interactions
- NDA/BLA/MAA submissions
- Cross-functional matrix leadership
- People leadership
- Translational and biomarker strategy
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
Revolution Medicines on Regulatory Jobs
- 40
- Open roles
- 32
- Distinct roles
- 3
- Locations
By discipline
- Clinical25 63%
- Regulatory7 18%
- Quality7 18%
By level
- Director28 70%
- Manager9 23%
- Senior & Principal3 8%
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Global Development Lead (GDL), Clinical Development at Revolution Medicines
Open until filled. $369K–$424K a year, employer provided.