New · posted Oct 31
Tango Therapeutics · Biotechnology
Director, Clinical Sciences
- Boston, MA
- On-site
- Full-time
- Director
The role
Tango has an exciting opportunity to join the team as our Director, Clinical Sciences. This is a hands-on role with scientific contributions to one or more clinical development programs. The successful candidate will actively engage in the design, execution, analysis, and interpretation of clinical studies. You will ensure scientific rigor throughout study conduct, lead data review and analysis, and partner cross-functionally to advance clinical development programs. This role reports to the Executive Director, Clinical Sciences.
Your Role:
What you need
What You Bring
- MD, PhD, PharmD, MS within a relevant scientific discipline
- At least 10 years of experience in clinical science, or research
- At least 5 years of experience in oncology
- Demonstrated experience in designing and managing clinical trials, including knowledge of regulatory guidelines and GCP
- Strong analytical skills with proficiency in statistical analysis and interpretation of clinical data
- Excellent written and oral communication skills, with the ability to convey complex scientific concepts to diverse audiences
- Experience working in a fast-paced environment
Pay
$190,400 – $285,600 a year
Employer provided$190,400—$285,600 USD
Where you'll work
Boston, MAOn-siteOpen in Maps (opens in a new tab)
More jobs in Boston, MA
From the posting
About Tango Therapeutics
Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.
Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.
This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.
Tango is located at 201 Brookline Avenue, in the vibrant Fenway area of Boston, Massachusetts.
Summary
- Scientific contribution to one or more clinical programs to ensure the successful design, execution, and interpretation of clinical studies
- Provide scientific leadership throughout the design, execution, analysis, and interpretation of early- and late-stage oncology clinical trials
- Partner closely with Clinical Development physicians, Clinical Operations, Biostatistics, Clinical Pharmacology, Pharmacovigilance, Regulatory Affairs, Translational Medicine, and Medical Writing to ensure high-quality execution of clinical programs
- Contribute to the development and review of key clinical documents, including protocols, investigator brochures, informed consent forms, clinical study reports, clinical development plans, and regulatory briefing materials
- Interpret emerging clinical, safety, PK/PD, and biomarker data to inform study conduct, dose selection, expansion opportunities, and overall development strategy
- Contribute scientific expertise to regulatory submissions and health authority interactions
- Foster a collaborative, accountable, and scientifically rigorous culture within the Clinical Science function
- Perform additional duties and responsibilities as required
Equal opportunity, accessibility and legal noticesTango Therapeutics's statements, word for word
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 20% below the US median for Clinical Development roles at this level.
This roleEmployer provided
Director roles in Massachusetts40 roles publishing pay
Director roles in the US93 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $190,400 | — | $285,600 |
| Massachusetts (middle half) | $255,000 | $298,000 | $308,250 |
| All US (middle half) | $258,000 | $298,000 | $318,500 |
This role: Tango Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Development roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Development
The general path across 116 open Clinical Development roles on Regulatory Jobs, with the titles they carry most. Not Tango Therapeutics's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 8 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct2
- Collaboration and leadership2
- GMP and compliance1
- Lab testing and methods1
- Documentation and SOPs1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
Tango Therapeutics on Regulatory Jobs
- 7
- Open roles
- 7
- Distinct roles
- 1
- Locations
By discipline
- Clinical4 57%
- Quality3 43%
By level
- Director4 57%
- Manager2 29%
- Senior & Principal1 14%
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Director, Clinical Sciences at Tango Therapeutics
Open until filled. $190K–$286K a year, employer provided.