New · posted Nov 7
Revolution Medicines · Biotechnology
Senior Vice President, Late-Stage Clinical Development
- Redwood City, CA
- Hybrid
- Full-time
- VP & Executive
The role
The Senior Vice President, Late-Stage Clinical Development is one of the most visible and influential leadership roles in the company. Reporting to the Chief Medical Officer and sitting at the top of the late-stage clinical development organization, this executive plays a key role in shaping how the portfolio evolves. The person in this seat drives the future value of the company from a compound perspective.
The role arrives at an inflection point. With the first medicine approved and multiple registrational programs running in parallel, the company is moving from a single approved product to a multi-asset, multi-indication late-stage portfolio. This leader drives the overall clinical development strategy, maps out the plan that carries the portfolio forward in partnership with the Chief Medical Officer, and owns the registrational and Phase 3 programs across every asset. The Global Development Team Leads across the portfolio report to this executive.
Much of the substance of the job is working through the Global Development Team Leads to shape the trials, interpret emerging data, and decide how to change standard of care in tumors that have resisted it. The leader is also accountable for the structure and development of the late-stage organization: hiring and developing team leads who build their own teams, and aligning clinical scientists to the programs they support.
Visibility extends well beyond the development organization. This executive works directly with the Chief Medical Officer and Chief Development Officer on portfolio strategy, represents Revolution Medicines externally with clinical collaboration partners, with the potential to co-chair a joint steering or joint development committee, and can take leadership of a disease-area franchise. This is intended as a long-term seat, with scope expected to grow as the organization and the portfolio expand.
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
What you need
Required Skills, Experience and Education
MD or MD/PhD, trained as a medical oncologist.
Substantial late-stage oncology development experience, including accountability for registrational and Phase 3 programs and global regulatory filings.
Depth in pancreatic, colorectal or lung cancer strongly preferred.
Track record leading development teams across multiple concurrent assets.
Demonstrated ability to build and structure a clinical development organization, including hiring program leaders and layering teams beneath them.
Strong scientific judgment and the credibility to guide experienced development leaders.
Effective operating in a fast-moving, evolving organization, and comfortable building alignment across senior stakeholders
Motivated by pipeline impact and the opportunity to change standard of care in difficult tumors.
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Base Pay Salary Range
$419,000—$523,000 USD
What you'll do
Drive the late-stage clinical development strategy across the RAS(ON) portfolio and map it into an integrated company development plan with the Chief Medical Officer.
Own registrational and Phase 3 trials across all programs and assets, from design through readout and submission support.
Shape indication sequencing, study design, endpoint selection and combination strategy with research, regulatory, biometrics and commercial leadership.
Lead, develop and grow the Global Development Team Leads, and guide the construction and defense of their clinical development plans.
Build a late-stage organization with clear program ownership, structured so that team leads hire and lead their own teams.
Partner with regulatory affairs on global filings, health authority interactions and lifecycle planning.
Partner with the Chief Medical Officer and Chief Development Officer on portfolio strategy and prioritization.
Represent the company with clinical collaboration partners, with the potential to co-chair a joint steering or joint development committee.
Engage investigators, key opinion leaders and the broader oncology community on the company's late-stage programs and data.
Pay and benefits
$419,000 – $523,000 a year
Employer providedCompetitive cash compensation
Equity awards
Strong benefits
Learning and development opportunities
Where you'll work
Redwood City, CAHybridOpen in Maps (opens in a new tab)
More jobs in Redwood City, CAEqual opportunity, accessibility and legal noticesRevolution Medicines's statements, word for word
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Job intelligence
The context around this role
Live data · November 7, 2026
Salary intelligence
How the pay compares
This role's midpoint is 18% above the US median for Clinical Development roles at this level.
This roleEmployer provided
VP & Executive roles in the US15 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $419,000 | — | $523,000 |
| All US (middle half) | $345,500 | $400,000 | $415,500 |
This role: Revolution Medicines's own published range. Comparisons: the base pay employers published on open Clinical Development roles at the same level on Regulatory Jobs, November 7, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Development
The general path across 283 open Clinical Development roles on Regulatory Jobs, with the titles they carry most. Not Revolution Medicines's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 27 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership12
- Clinical trial conduct6
- Documentation and SOPs2
- Regulatory submissions2
- Investigations and CAPA1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Development work in biotechnology, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trials
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
Revolution Medicines on Regulatory Jobs
- 42
- Open roles
- 42
- Distinct roles
- 2
- Locations
By discipline
- Clinical27 64%
- Quality8 19%
- Regulatory7 17%
By level
- Director28 67%
- Manager10 24%
- Senior & Principal3 7%
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Senior Vice President, Late-Stage Clinical Development at Revolution Medicines
Open until filled. $419K–$523K a year, employer provided.