New · posted Oct 15
Nurix Therapeutics · Biotechnology
Senior Scientist, Analytical Development and Quality Control - Early Phase
- Brisbane, CA
- On-site
- Full-time
- Senior & Principal
Open until filled
The role
Company
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.
Nurix Therapeutics seeks an experienced Senior Scientist to join the Analytical Development and Quality Control group. The Senior Scientist will lead analytical and QC activities in IND-enabling and early phase clinical studies. The Senior Scientist will develop analytical test methods, characterize drug substance and drug product attributes, identify and characterize technical risk, and collaborate in risk mitigation work. The Senior Scientist will oversee and execute analytical development, validation, and testing both internally and at external CDMO/CRO partners and author relevant sections of regulatory filings.
The ideal candidate must have expertise in chromatographic method development, stability studies, and phase-appropriate validation and control. The ideal candidate should have a record of contribution to first-in-human INDs and experience in vendor oversight..
This position is onsite at Nurix headquarters in Brisbane, CA.
What you need
- Advanced degree in a relevant discipline (Chemistry, Pharmaceutics, or related field)
- Senior Scientist: BS/MS degree with 14+ years or PhD with 8+ years of industrial CMC experience
- Expertise in HPLC method development is essential
- Additional experience in techniques such as gas chromatography, NMR, mass spectrometry, particle size analysis, solid state characterization, dissolution, ICP-MS/OES, and/or FTIR
- Experience in analytical method development and validation
- Experience in management of analytical activities at CDMOs/CROs
- Solid understanding of control strategy, method validation, and retest/expiry
- Experience managing stability programs, reference standards, and retest/expiry
- Familiarity with ICH guidelines, cGMPs, and pharmacopeial chapters
- Familiarity with deviation management and change control
- Ability to critically interpret data and articulate technical concepts in multidisciplinary settings
- Ability to ensure assigned activities are completed in satisfaction of project timelines
- Strong interpersonal skills that foster collaboration within and outside of the organization
- Ability to travel domestically and internationally
What you'll do
- Characterization of drug substance and drug product attributes, identification of technical risks, and collaboration towards risk mitigation strategy
- Method development for and analytical characterization of drug substances, drug products, and product stability
- Management and/or execution of method development internally and at CDMOs/CTLs
- Management of method validation, QC testing, and reference standards at CDMOs/CTLs
- Management of forced degradation, long term stability, and predictive stability studies
- Contribution to OOS/OOE/OOT investigations
- Critical review of data, protocols, reports, specifications, and other documentation
- Trending stability data and establishing retest periods/shelf life using statistical methods
- Collaboration in the development of material control strategies and specifications
- Follow cGMP requirements and internal SOPs
Pay
$162,000 – $186,000 a year
Employer providedWhere you'll work
Brisbane, CAOn-siteOpen in Maps (opens in a new tab)
More jobs in Brisbane, CA
From the posting
About Nurix
Fit with Nurix Culture and Values
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
Job intelligence
The context around this role
Live data · October 15, 2026
Salary intelligence
How the pay compares
This role's midpoint is 83% above the US median for Quality Control roles at this level.
This roleEmployer provided
Senior & Principal roles in California6 roles publishing pay
Senior & Principal roles in the US49 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $162,000 | — | $186,000 |
| California (middle half) | $91,375 | $95,500 | $112,375 |
| All US (middle half) | $78,500 | $95,000 | $108,500 |
This role: Nurix Therapeutics's own published range. Comparisons: the base pay employers published on open Quality Control roles at the same level on Regulatory Jobs, October 15, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Quality Control
The general path across 275 open Quality Control roles on Regulatory Jobs, with the titles they carry most. Not Nurix's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 28 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Lab testing and methods13
- Validation and qualification5
- Collaboration and leadership5
- Documentation and SOPs4
- Investigations and CAPA2
- GMP and compliance1
- Regulatory submissions1
- Quality systems and risk1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
- FDA21 CFR Parts 210 and 211(official source, opens in a new tab)FDA current good manufacturing practice for finished pharmaceuticals
- FDAFDA OOS guidance(official source, opens in a new tab)Investigating Out-of-Specification (OOS) Test Results for Pharmaceutical Production
- ICHICH quality guidelines(official source, opens in a new tab)Q1 stability, Q2(R2) analytical validation, Q7, Q9 risk management, Q10 quality systems
- FDAFDA IND(official source, opens in a new tab)Investigational New Drug applications
Company hiring pulse
Nurix on Regulatory Jobs
- 11
- Open roles
- 11
- Distinct roles
- 1
- Locations
By discipline
- Quality6 55%
- Regulatory5 45%
By level
- Director7 64%
- Manager3 27%
- Senior & Principal1 9%
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Senior Scientist, Analytical Development and Quality Control - Early Phase at Nurix
Open until filled. $162K–$186K a year, employer provided.