New · posted Nov 7
Revolution Medicines · Biotechnology
Senior Manager, Stability Management, Analytical Development and Quality Control
- Redwood City, CA
- Hybrid
- Full-time
- Manager
The role
Playing a critical role as the subject matter expert (SME) on stability management, the position will be responsible for management of outsourced stability studies. The Sr. Manager, stability is a self-motivated individual who works as a member of an integrated team from design, management, and evaluation stability studies outsourced to contract organization. This individual should have the breadth of experience and knowledge required to support commercial, late and early clinical development stage. This individual should have good understanding of ICH and cGMP guidelines and the ability to contribute to global regulatory filings for stability.
Coordinate stability activities, including but not limited to monitor schedule, data entry, review and presentations/reports.
Track stability studies, maintain stability database.
Author and / or review stability related documents, including protocol, report, and memos.
Work cross functionally with CMC, quality, regulatory, clinical and related teams to achieve stability objectives.
Compile stability study results, perform trend and statistical analyses, and prepare reports to support retest/shelf-life date extensions and storage condition recommendations.
Partner with quality during stability quality events (QEs) or investigations and implementation of CAPAs at contract organization.
Manage sample shipment, inventory tracking, and chain of custody for stability studies.
Support, author CMC stability documentation for IND, NDA, AR and IMPD filings, covering all phases of clinical development and commercial activities by ensure completeness and accuracy of stability data.
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
What you need
Required Skills, Experience and Education
PhD in Chemistry, Pharmaceutical Sciences, or related discipline with 8+ years of industry experience; or MS with 10+ years, or BS with 12+ years.
6+ years in stability management or relevant experience within pharmaceutical or biotech industry.
Strong knowledge of GMP regulations, quality systems, ICH guidelines, and regulatory expectations (FDA, EMA, etc.)
Extensive experience managing contract organization and working in a virtual development model.
Excellent leadership, people/team management, project management, and cross-functional collaboration skills.
Strong problem-solving skills with strategic and technically sound decision-making ability.
Excellent written and verbal communication skills and interpersonal skills.
Energetic, team-oriented, and adaptable to a fast-paced, dynamic environment.
Preferred Skillsnice to have
Experience with small molecule oncology drug development.
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Base Pay Salary Range
$164,000—$205,000 USD
Pay and benefits
$164,000 – $205,000 a year
Employer providedCompetitive cash compensation
Equity awards
Strong benefits
Learning and development opportunities
Where you'll work
Redwood City, CAHybridOpen in Maps (opens in a new tab)
More jobs in Redwood City, CAEqual opportunity, accessibility and legal noticesRevolution Medicines's statements, word for word
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Job intelligence
The context around this role
Live data · November 7, 2026
Salary intelligence
How the pay compares
This role's midpoint is 61% above the US median for Quality Control roles at this level.
This roleEmployer provided
Manager roles in California11 roles publishing pay
Manager roles in the US30 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $164,000 | — | $205,000 |
| California (middle half) | $104,000 | $128,500 | $152,000 |
| All US (middle half) | $104,000 | $114,250 | $138,375 |
This role: Revolution Medicines's own published range. Comparisons: the base pay employers published on open Quality Control roles at the same level on Regulatory Jobs, November 7, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Quality Control
The general path across 248 open Quality Control roles on Regulatory Jobs, with the titles they carry most. Not Revolution Medicines's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 24 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Lab testing and methods10
- Collaboration and leadership6
- Documentation and SOPs4
- Clinical trial conduct3
- GMP and compliance2
- Investigations and CAPA1
- Regulatory submissions1
- Quality systems and risk1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Quality Control work in biotechnology, led by the three this posting names, each linked to the agency or standards body that publishes it.
- FDA21 CFR Parts 210 and 211(official source, opens in a new tab)FDA current good manufacturing practice for finished pharmaceuticalsNamed in the posting
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trialsNamed in the posting
- FDA21 CFR Part 314(official source, opens in a new tab)Applications for FDA approval to market a new drug (NDA and ANDA)Named in the posting
- USPUSP–NF(official source, opens in a new tab)US Pharmacopeia general chapters and monographs, such as <61> bioburden, <85> endotoxin, <1225> validation
- FDAFDA OOS guidance(official source, opens in a new tab)Investigating Out-of-Specification (OOS) Test Results for Pharmaceutical Production
- FDAFDA data integrity guidance(official source, opens in a new tab)Data Integrity and Compliance With Drug CGMP: Questions and Answers
- ICHICH Q1 stability testing(official source, opens in a new tab)Stability testing of drug substances and drug products
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- ICHICH Q2(R2) and Q14(official source, opens in a new tab)Validation and development of analytical procedures
- FDAFDA analytical procedures guidance(official source, opens in a new tab)Analytical Procedures and Methods Validation for Drugs and Biologics
- EDQMEuropean Pharmacopoeia(official source, opens in a new tab)The Ph. Eur. quality standards for medicines in Europe, published by the EDQM
- ICHICH Q3 impurities(official source, opens in a new tab)Impurities in drug substances and products, residual solvents and elemental impurities
- FDAFDA aseptic processing guidance(official source, opens in a new tab)Sterile Drug Products Produced by Aseptic Processing: Current Good Manufacturing Practice
- ISOISO 14644-1(official source, opens in a new tab)Cleanroom air cleanliness classification by particle concentration
- EUEU GMP (EudraLex Volume 4)(official source, opens in a new tab)The EU's good manufacturing practice rules, including Annex 1 sterile and Annex 15 validation
- FDA21 CFR Parts 600 to 680(official source, opens in a new tab)FDA standards for biological products, from licensing to lot release
Company hiring pulse
Revolution Medicines on Regulatory Jobs
- 42
- Open roles
- 42
- Distinct roles
- 2
- Locations
By discipline
- Clinical27 64%
- Quality8 19%
- Regulatory7 17%
By level
- Director28 67%
- Manager10 24%
- Senior & Principal3 7%
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Senior Manager, Stability Management, Analytical Development and Quality Control at Revolution Medicines
Open until filled. $164K–$205K a year, employer provided.