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New · posted Oct 31

Revolution Medicines · Biotechnology

Senior Director, Clinical Operations, Global Clinical Vendor Contracts & Budgets

  • Redwood City, CA
  • Hybrid
  • Full-time
  • Director
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EmploymentFull-time
DeadlineOpen until filled

The role

This is a unique opportunity for a Clinical Operations Professional who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in negotiation, execution, and management of clinical trial vendor agreements budgets. The leadership role ensures alignment with strategic objectives, regulatory requirements, and study timelines as well as bringing deep expertise in managing complex trials, contract negotiations, budget development, risk management, and cross-functional collaboration to contribute to the highest quality with on time delivery of RevMed’s clinical studies.  A member of the Clinical Operations team Leading the Contracts and Outsourcing for all vendor relationships within Clinical Development, the Sr Director Global Vendor Outsourcing will lead the strategic identification and selection process with the teams for vendors and CROs, including scope specifications for clinical programs, and will work closely with the Sr. Director of Clinical Business Operations to support the financial and business negotiation process.  This role will play an integral role in the execution of the Company's clinical studies using CROs and vendors of the highest quality with on time delivery. The successful candidate needs to have the ability to manage the vendor outsourcing team, as well as develop robust systems and processes required for the team for seamless communication with the Clinical Operations team. Key Responsibilities include:

  • Develop and execute the global clinical outsourcing strategy, aligning vendor governance, contracting, and operational frameworks with Revolution Medicines' corporate objectives and clinical development priorities.

  • Provide strategic leadership and oversight for the Global Clinical Vendor Contracts function, driving operational excellence, scalable processes, standardized policies, and continuous improvement across the end-to-end contract lifecycle.

  • Serve as the executive sponsor for global clinical vendor relationships, establishing governance models, performance metrics (KPIs), preferred provider strategies, and risk management practices that optimize quality, cost, and delivery.

  • Lead cross-functional partnerships with Clinical Operations, Biometrics, Data Management, Safety, Regulatory, Quality, Finance, Legal, and IT to develop outsourcing strategies, negotiate commercial terms, and ensure seamless execution of clinical programs.

  • Direct strategic sourcing, RFP development, vendor evaluation, selection, and contract negotiations, including Master Service Agreements, work orders, change orders, consulting agreements, and clinical budgets.

  • Build and sustain high-performing vendor partnerships through proactive performance management, compliance oversight, issue resolution, and executive-level governance, ensuring vendors consistently meet contractual and operational expectations.

  • Anticipate, assess, and resolve complex business, operational, and vendor relationship challenges, serving as the senior escalation point for critical outsourcing and contract execution issues.

  • Champion innovation by monitoring industry trends, benchmarking best practices, and implementing new technologies, contracting models, and process improvements that enhance efficiency, scalability, and business performance.

  • Lead, mentor, and develop a high-performing Vendor Contracts organization by fostering collaboration, accountability, strategic thinking, and continuous professional growth while building organizational capabilities for future business needs.

  • Ensure appropriate vendor qualification, regulatory compliance, financial stewardship, and contractual risk mitigation through strong collaboration with Quality Assurance, Legal, Finance, and other key stakeholders.

  • Represent Global Clinical Vendor Outsourcing in senior leadership discussions, contributing strategic expertise, data-driven insights, and executive recommendations that support enterprise decision-making and successful delivery of the clinical development portfolio.

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

What you need

Required Skills, Experience and Education

  • BS, plus 17+ years of experience or equivalent and 10+ years at a leadership role. Advanced degree desirable: Master, 15+ years experience and 8+ years leadership or Doctoral,  13+ years experience and 6+ years leadership.

  • Expertise in large, multi-site, early/late phase and postmarketing Oncology clinical trials.

  • Experience working in growing companies or departments that have created successful processes.

  • Must demonstrate clear understanding of Clinical contracting and budget process.

  • Excellent organizational and time management skills along with strong attention to detail. Proven ability to handle multiple tasks efficiently and effectively.

  • Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.

  • Experience leading strategic change management initiatives across clinical operations or equivalent.

  • Excellent interpersonal, verbal, and written communication skills, with ability to interact with colleagues and partners at all levels of experience.

  • Proven understanding in global site budget and contract negotiations in order to achieve optimal results and develop plans to meet strategic and operational targets in alignment with RevMed.

  • Ability to produce, interpret and share complex performance information and communicate it to a wide variety of audiences.

  • Experience with hiring, training, developing, mentoring, and motivating team members to the highest level of performance.

  • An innovative, driven, and effective person with a "can do" attitude.

  • A goal-oriented person who can plan for the long-term and execute stated objectives.

  • Travel may be required (~25%).

Preferred Skillsnice to have

  • Familiarity working with financial and legal systems/portals.

  • Knowledge and/or familiarity with Ex-US region(s) clinical trial operations.

  • Working knowledge of applicable regulatory, ICH and GCP.

  • Global Project Level Budget Builds.

  • Advanced knowledge of Microsoft Word, Excel, PowerPoint and Smartsheet.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$244,000—$305,000 USD

Pay and benefits

$244,000 – $305,000 a year

Employer provided
How this compares
  • Competitive cash compensation

  • Equity awards

  • Strong benefits

  • Learning and development opportunities

Where you'll work

Redwood City, CAHybridOpen in Maps (opens in a new tab)

More jobs in Redwood City, CA
Equal opportunity, accessibility and legal noticesRevolution Medicines's statements, word for word

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
 
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
 
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

Job intelligence

The context around this role

Live data · October 31, 2026

Salary intelligence

How the pay compares

This role's midpoint is 18% above the US median for Clinical Operations roles at this level.

This roleEmployer provided

$244,000 to $305,000 a year

Director roles in California5 roles publishing pay

Middle half $233,000 to $244,000, median $244,000

Director roles in the US20 roles publishing pay

Middle half $216,250 to $244,000, median $233,000
Annual base pay
Annual base payLowMedianHigh
This role$244,000—$305,000
California$233,000$244,000$244,000
All US$216,250$233,000$244,000

This role: Revolution Medicines's own published range. Comparisons: the base pay employers published on open Clinical Operations roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.

Career trajectory

Where this role sits in Clinical Operations

The general path across 42 open Clinical Operations roles on Regulatory Jobs, with the titles they carry most. Not Revolution Medicines's own promotion track.

  1. Earlier

    Associate & Specialist

    Often: Clinical Trial Associate · Clinical Study Start-Up Associate

    $92K median7 open
  2. Earlier

    Senior & Principal

    Often: Sr. Clinical Trial Associate · Senior Clinical Operations Contractor

    $121K median7 open
  3. One step back

    Manager

    Often: Clinical Operations Senior Manager · Clinical Trials Manager

    $168K median6 open
  4. This role

    Director

    Often: Director, Clinical Operations · Program Lead II, Clinical Program Development

    $233K median21 open
  5. Next step

    VP & Executive

    Often: Vice President, Clinical Operations

Skills DNA

What this role leans on

How many of the posting's 37 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.

GMP and compliance: 3 linesValidation and qualification: 1 lineQuality systems and risk: 4 linesData and digital systems: 2 linesClinical trial conduct: 5 linesCollaboration and leadership: 11 linesGMPValidationQuality systemsData systemsClinical trialsTeamwork
  • Collaboration and leadership11
  • Clinical trial conduct5
  • Quality systems and risk4
  • GMP and compliance3
  • Data and digital systems2
  • Validation and qualification1

Company hiring pulse

Revolution Medicines on Regulatory Jobs

40
Open roles
32
Distinct roles
3
Locations

By discipline

  • Clinical25 63%
  • Regulatory7 18%
  • Quality7 18%

By level

  • Director28 70%
  • Manager9 23%
  • Senior & Principal3 8%
See all 40 Revolution Medicines roles

More roles at Revolution Medicines

All 40 Revolution Medicines roles

Similar Clinical Operations roles elsewhere

Senior Director, Clinical Operations, Global Clinical Vendor Contracts & Budgets at Revolution Medicines

Open until filled. $244K–$305K a year, employer provided.

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