New · posted Nov 6
Deciphera Pharmaceuticals · Pharmaceuticals
Senior Clinical Project Manager
- Remote, US
- Remote
- Full-time
- Manager
The role
Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together. Learn more about Deciphera, a member of Ono Pharmaceutical Co., Ltd., by visiting our website: https://deciphera.com
The Senior Clinical Project Manager leads the execution of complex global clinical studies, providing hands-on operational leadership across study teams and external partners. This role is responsible for driving study execution, managing timelines and budgets, and ensuring trials are delivered with quality and in compliance with applicable requirements.
The ideal candidate brings strong later-stage clinical trial experience, ideally including Phase III, and is comfortable taking ownership, working through challenges, and knowing when to engage others for support.
Role Specific Additional Information
Due to the global nature of the role, there may occasionally be a need for early-morning or evening meetings to accommodate teams and partners across time zones.
Travel of approximately 25% may be required, including travel to Boston approximately twice per year, as well as attendance at relevant conferences or study-related meetings.
Deciphera believes in providing a fair, equitable, and competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
What you need
Preferred Capabilitiesnice to have
- Phase III global study experience.
- Oncology or rare disease clinical development experience.
- Experience with eTMF, EDC, IWRS, and RBQM platforms.
- Experience managing clinical study budgets and contracts.
- Experience within a fast-paced biotechnology environment.
- PMP certification or equivalent project management training.
What you'll do
Clinical Trial Leadership & Execution
- Lead the planning, execution, and delivery of assigned global clinical studies, with responsibility for timelines, budgets, quality, and overall operational execution.
- Identify and address operational risks and challenges to keep studies on track.
Cross-Functional Leadership
- Lead cross-functional study teams, driving collaboration, accountability, decision-making, and problem-solving.
- Partner across Clinical Operations, Data Management, Regulatory, Clinical Supply, and other functions to support global study execution.
CRO & Vendor Management
- Oversee CROs and external vendors, monitoring performance and ensuring alignment with study timelines, budgets, quality expectations, and contractual obligations.
Stakeholder Communication & Operational Excellence
- Communicate study progress, risks, and key decisions clearly to internal stakeholders and Clinical Operations leadership.
- Contribute to Clinical Operations processes and ways of working that support efficient, high-quality study execution.
Other duties and responsibilities as assigned
- Bachelor’s degree in health science or a related field and 8+ years of clinical research experience, including meaningful responsibility for managing complex clinical trials.
- Strong global clinical trial and later-stage development experience, ideally including Phase III. Candidates with substantial experience leading large, complex Phase II studies will also be considered.
- Demonstrated ability to lead and influence cross-functional study teams.
- Hands-on experience managing CROs and vendors and proactively addressing operational risks.
- Strong working knowledge of GCP, ICH, FDA, and applicable global clinical trial requirements.
- Strong communication and problem-solving skills, with the ability to work independently, advocate for what is needed, and recognize when to engage others for support.
Pay and benefits
$138,000 – $168,000 a year
Employer providedCompetitive salary and annual bonus.
Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
Generous parental leave and family planning benefits.
Outstanding culture and opportunities for personal and professional growth.
Equal opportunity, accessibility and legal noticesDeciphera Pharmaceuticals's statements, word for word
EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.
Job intelligence
The context around this role
Live data · November 6, 2026
Salary intelligence
How the pay compares
This role's midpoint is 6% below the US median for Clinical Project Management roles at this level.
This roleEmployer provided
Manager roles in the US21 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $138,000 | — | $168,000 |
| All US (middle half) | $153,500 | $163,000 | $176,000 |
This role: Deciphera Pharmaceuticals's own published range. Comparisons: the base pay employers published on open Clinical Project Management roles at the same level on Regulatory Jobs, November 6, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Project Management
The general path across 39 open Clinical Project Management roles on Regulatory Jobs, with the titles they carry most. Not Deciphera's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 25 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct11
- Collaboration and leadership10
- GMP and compliance2
- Data and digital systems1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Project Management work in pharmaceuticals, led by the one this posting names, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trialsNamed in the posting
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
Deciphera on Regulatory Jobs
- 9
- Open roles
- 9
- Distinct roles
- 2
- Locations
By discipline
- Clinical9 100%
By level
- Director6 67%
- Manager3 33%
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Senior Clinical Project Manager at Deciphera
Open until filled. $138K–$168K a year, employer provided.