New · posted Oct 31
Deciphera Pharmaceuticals · Biotechnology
Medical Director, Clinical Development (Neurology)
- Remote, US
- Remote
- Full-time
- Director
The role
Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK® (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.
The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together.
Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.
The medical director will provide clinical development leadership at the study level for one or more clinical stage assets in early and/or late development. To achieve development goals this individual will foster collaboration with allied functions through outstanding communication, collaboration and coordination. Depending on business needs, the role could include mentorship and management of one or more clinical scientists as well as contribution to business development and continuous improvement activities.
What you need
Preferred Capabilitiesnice to have
- Board certification in Nuerology
- Experience in phases 3 of clinical development
- Experience interacting with FDA and regulatory agencies outside of the USA
- Experience in basic or translational science
Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
What you'll do
- Provide clinical development leadership to one or more programs 75%
- Contribute to clinical development strategy in alignment with enterprise goals and management
- Serve as medical monitor for one or more studies
- Perform ongoing clinical trial data review and cleaning in collaboration with clinical science and pharmacovigilance
- Attend and contribute to study team meetings
- Present clinical trial findings to management
- Author clinical documents (protocol, investigator brochure)
- Author clinical portions of regulatory documents (IND, CTA, NDA, MAA or equivalent)
- Develop and manage relationships with key opinion leaders for clinical programs
- Organize, manage and lead Steering Committees and contribute to Strategic or Clinical Advisory Boards
- Contribute to writing of manuscripts, publications, or other documents intended for external audiences
- Contribute in an active and ongoing manner to the scientific, clinical, and commercial development of current and future product candidates
- Contribute to company culture and growth 25%
- Foster communication, collaboration and coordination with other functions
- Contribute to maximizing synergistic collaboration between Ono and Deciphera
- Contribute to assessment of new internal or external targets by outlining clinical challenges and opportunities
- Support Medical Affairs activities as needed
- Participate in and/or coordinate cross-functional continuous improvement projects
- Act as an internal resource for functions requiring clinical input on select drug(s) including primary point of contact for clinical trial staff at study sites for clinical issues as well as regulatory, safety and other functions
- Medical Degree or equivalent with 8+ years of combined relevant academic and industry experience (post-medical school), including 3+ years of work on clinical trials.
- Experience with clinical trial design, conduct, and medical monitoring
- Understanding of GCP/ICH and regional/local regulations
- Familiarity with data review/analytics tools (Rave, J-Review, Spotifre, etc)
- Outstanding leadership, team, presentation, written and oral skills
- Collaborative and flexible in personal interactions at all levels of the company
- Ability to work proactively and effectively, with exceptional creative problem-solving skills
- Excellent strategic planning, organizational and communication skills
- Willingness to accommodate meetings across time zones as needed for project success
- Up to 30% travel
Pay and benefits
$248,000 – $341,000 a year
Employer providedDeciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $248,000-$341,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.
Competitive salary and annual bonus.
Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
Generous parental leave and family planning benefits.
Outstanding culture and opportunities for personal and professional growth.
Equal opportunity, accessibility and legal noticesDeciphera Pharmaceuticals's statements, word for word
EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 1% below the US median for Clinical Development roles at this level.
This roleEmployer provided
Director roles in Massachusetts40 roles publishing pay
Director roles in the US93 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $248,000 | — | $341,000 |
| Massachusetts (middle half) | $255,000 | $298,000 | $308,250 |
| All US (middle half) | $258,000 | $298,000 | $318,500 |
This role: Deciphera Pharmaceuticals's own published range. Comparisons: the base pay employers published on open Clinical Development roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Development
The general path across 116 open Clinical Development roles on Regulatory Jobs, with the titles they carry most. Not Deciphera's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 38 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership13
- Clinical trial conduct11
- Documentation and SOPs5
- Quality systems and risk2
- GMP and compliance1
- Investigations and CAPA1
- Regulatory submissions1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
- ICHICH quality guidelines(official source, opens in a new tab)Q1 stability, Q2(R2) analytical validation, Q7, Q9 risk management, Q10 quality systems
- ICHICH E6 good clinical practice(official source, opens in a new tab)The international standard for the conduct of clinical trials
- FDAFDA IND(official source, opens in a new tab)Investigational New Drug applications
- FDAFDA NDA(official source, opens in a new tab)New Drug Applications
Company hiring pulse
Deciphera on Regulatory Jobs
- 8
- Open roles
- 7
- Distinct roles
- 2
- Locations
By discipline
- Clinical6 75%
- Regulatory2 25%
By level
- Director4 50%
- Manager4 50%
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Medical Director, Clinical Development (Neurology) at Deciphera
Open until filled. $248K–$341K a year, employer provided.