New · posted Nov 1
Edwards Lifesciences · Medical Devices
Principal, Clinical Programming, Surgical
- Irvine, CA
- Hybrid
- Full-time
- Senior & Principal
The role
Imagine how your ideas and expertise can change a patient’s life. We generate extensive clinical evidence to demonstrate the effectiveness and safety of our innovations and how our products transform patients’ lives. As part of our Clinical Affairs team, you’ll hone your scientific curiosity and passion for evaluating data to increase access to pioneering technologies for patients in need. In close partnership with principal investigators, dedicated medical professionals, patient advocacy groups, and regulatory authorities, you will drive the evidence needed to optimize patient outcomes.
Dedicated to innovation, our Surgical business unit is focused on identifying and solving critical, unmet needs in cardiac surgery. In understanding the challenges of open-heart surgery, we partner with surgical teams to deliver modern technologies intended to enhance patients’ quality of life and expand their potential treatment opportunities. It’s our driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey.
What you need
What you will need (Required)
- Bachelor's Degree and a minimum of 6 years experience in clinical research, data management, software programming or related field or equivalent work experience based on Edwards criteria
- Extensive experience with EDC (Electronic Data Capture) systems; Medidata programming experience
What else we look for (Preferred)nice to have
- Master's Degree and a minimum of 5 years experience in clinical research, data management, software programming or related field or equivalent work experience based on Edwards criteria OR a Ph.D. and a minimum of 2 years experience in clinical research, data management, software programming or related field or equivalent work experience based on Edwards criteria
- Expert knowledge in creating new and maintaining existing Medidata custom functions in C# or SQL.
- Proven successful project management skills
- Proven expertise in both Microsoft Office Suite, including advanced Excel and CDM (Clinical Data Management) systems
- Excellent documentation and communication skills and interpersonal relationship skills including negotiating and relationship management skills with ability to drive achievement of objectives
- Good presentation and facilitation skills
- Ability to translate technical information to cross-functional teams
- Extensive knowledge of own area within the organization while contributing to the development of new concepts, techniques, and standards
- Extensive knowledge and understanding of policies, procedures and guidelines relevant in the development of clinical databases
- Extensive knowledge of processes and procedures in clinical data management
- Extensive knowledge of relational databases, systems, and programming languages
- Extensive knowledge of clinical programming as it relates to business processes
- Ability to manage competing priorities in a fast-paced environment
- Represents leadership on sections of projects within a specific area interfacing with project managers and team members
Aligning our overall business objectives with performance, we offer competitive salaries, performance-based incentives, and a wide variety of benefits programs to address the diverse individual needs of our employees and their families.
What you'll do
How you will make an impact
- Provide technical expertise in clinical programming functional area and lead in the development of clinical databases, and tools and programs for data validation checks, and clinical trial reporting in collaboration with key stakeholders
- Lead cross functional teams in the design and delivery of complex functional modules and provide clinical programming expertise regarding clinical trials, protocols, and case report forms
- Lead the development of specifications for systems and/or processes, system upgrades/enhancements and integration; and engage IT to deliver higher level support to users
- Develop and present high level technical training to end-users, including providing guidance to lower-level Clinical Programmers in their training program development
- Identify resource needs for database implementation and participate in the evaluation of external resources/vendors
- Manage daily service providers’ activities for outsourced systems and services used in clinical trials
- Participate in the creation and revision of new or existing SOPs, work instructions, workflow, forms, and templates to ensure clinical systems and activities are in compliance with the regulatory and company requirements
Pay and benefits
$132,000 – $186,000 a year
Employer provided
For California, the base pay range for this position is $132,000 - $186,000 (highly experienced).
The pay for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience). Applications will be accepted while this position is posted on our Careers website.
Competitive salaries
Performance-based incentives
Wide variety of benefits programs
Where you'll work
Irvine, CAHybridOpen in Maps (opens in a new tab)
More jobs in Irvine, CAEqual opportunity, accessibility and legal noticesEdwards Lifesciences's statements, word for word
Edwards is an Equal Opportunity/Affirmative Action employer including protected Veterans and individuals with disabilities.
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 15% above the US median for Clinical Data Management roles at this level.
This roleEmployer provided
Senior & Principal roles in the US14 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $132,000 | — | $186,000 |
| All US (middle half) | $127,375 | $138,750 | $150,625 |
This role: Edwards Lifesciences's own published range. Comparisons: the base pay employers published on open Clinical Data Management roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Data Management
The general path across 54 open Clinical Data Management roles on Regulatory Jobs, with the titles they carry most. Not Edwards Lifesciences's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 26 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership9
- Clinical trial conduct7
- Documentation and SOPs5
- Data and digital systems5
- GMP and compliance1
- Investigations and CAPA1
- Validation and qualification1
Company hiring pulse
Edwards Lifesciences on Regulatory Jobs
- 31
- Open roles
- 30
- Distinct roles
- 6
- Locations
By discipline
- Quality18 58%
- Regulatory7 23%
- Clinical6 19%
By level
- Senior & Principal20 65%
- Associate & Specialist6 19%
- Director3 10%
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Principal, Clinical Programming, Surgical at Edwards Lifesciences
Open until filled. $132K–$186K a year, employer provided.