New · posted Nov 1
Genentech · Biotechnology
Head, US Patient Safety
- South San Francisco, CA
- On-site
- Full-time
- VP & Executive
The role
In this role, core responsibilities will include:
- Strategy: Lead the Affiliate Patient Safety strategy, collaborating with cross-functional leaders to prioritize initiatives that maximize patient and business impact. Additionally, serve on the IPS Leadership Team to co-own the strategic vision, governance, and collective performance of the broader IPS organization.
- PV System: Maintain holistic oversight of the local PV system to ensure strict compliance, operational efficiency, and inspection readiness, thereby safeguarding the company’s license to operate.
- Safety Risk Management: Ensure product safety launch readiness, aligning global safety solutions with therapeutic strategies and driving local risk minimization efforts that improve patient outcomes.
- Safety Communication: Lead strategies to communicate and educate on safety risks in context, ensuring transparent and timely safety communications to healthcare professionals, patients, and external stakeholders, in partnership with US Medical and other functions.
- Safety Insights: Drive the systematic collection, analysis, and sharing of safety insights aligned with disease area goals, leveraging digital solutions and real-world evidence as appropriate.
- People Leadership & Talent Pipeline: Provide solid-line leadership to the US Patient Safety Leadership Team, with overarching talent oversight, succession planning, and capability building across all US safety staff.
The Head of US Patient Safety is accountable for the overall strategic direction, operational execution, and holistic performance of the PV system for the USA, ensuring full alignment with International Patient Safety (IPS) priorities and business needs. Operating in close partnership with Genentech, the Head of US Patient Safety serves as the primary steward of the affiliate PV system and safety risk management.
What you need
- Medical degree (MD or equivalent) or higher degree in life science discipline (e.g., PharmD, PhD, MSc)
- Minimum of 12 years of experience in PV, clinical research/development, including 7+ years in senior Patient Safety leadership roles across complex regional or global environments.
- Minimum of 7 years of executive people leadership coaching, developing, and engaging large multi-layered teams and networks of leaders.
- Proven track record of operating with an enterprise-first mindset, demonstrating behaviors that consistently drive impact, influence strategy, and build capabilities beyond assigned regional borders.
- Executive presence and recognized authority influencing senior leadership across local and global organizations.
- Extensive experience engaging with major Tier-1 global Health Authorities and shaping international PV ecosystems
Relocation benefits are available for this posting
The expected salary range for this position based on the primary location of California is $282,000 - $523,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Pay
$282,000 – $523,600 a year
Employer providedIf you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Where you'll work
South San Francisco, CAOn-siteOpen in Maps (opens in a new tab)
More jobs in South San Francisco, CAEqual opportunity, accessibility and legal noticesGenentech's statements, word for word
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 16% above the US median for Clinical Safety & Pharmacovigilance roles at this level.
This roleEmployer provided
VP & Executive roles in the US11 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $282,000 | — | $523,600 |
| All US (middle half) | $346,500 | $346,500 | $366,500 |
This role: Genentech's own published range. Comparisons: the base pay employers published on open Clinical Safety & Pharmacovigilance roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Safety & Pharmacovigilance
The general path across 162 open Clinical Safety & Pharmacovigilance roles on Regulatory Jobs, with the titles they carry most. Not Genentech's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 16 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership6
- Quality systems and risk2
- GMP and compliance1
- Documentation and SOPs1
- Regulatory submissions1
- Clinical trial conduct1
Company hiring pulse
Genentech on Regulatory Jobs
- 26
- Open roles
- 25
- Distinct roles
- 6
- Locations
By discipline
- Quality15 58%
- Regulatory7 27%
- Clinical4 15%
By level
- Senior & Principal20 77%
- Director3 12%
- VP & Executive1 4%
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Head, US Patient Safety at Genentech
Open until filled. $282K–$524K a year, employer provided.