A Vertex scientist in a mask and lab coat working at a lab bench at the San Diego research site

New · posted Oct 13

Vertex Pharmaceuticals · Biotechnology

Director, Commercial Quality-Packaging and Labeling

Boston, MA
Hybrid
Full-time
Director

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Pay$185K–$277Ka year · employer provided

EmploymentFull-time

LocationBoston, MAHybrid

LevelDirector

FunctionQuality AssuranceQuality

Deadline

Closes Nov 12, 2026 · 30 days left

The role

The Quality Operations Director provides operational leadership for commercial resupply and lifecycle management of primary and secondary packaging and labeling across a global CMO network. The role translates strategy, capacity plans, and business priorities into an efficient operating model across global CMO portfolios.

The Director leads a risk-based quality oversight structure required to assure compliant, reliable, and uninterrupted commercial supply. The role leads a high-performing organization and serves as a senior Quality partner to CMO leadership, Vertex Sr Director of quality operations, Manufacturing &technical operations, Supply Chain, Regulatory, Launch/Technical Quality, and other internal and external stakeholders.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

What you need

Bachelor’s degree in a scientific or allied health field, or equivalent degree
Requires 10+ years of relevant work experience and 4+ years of management experience, or the equivalent combination of education and experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

KNOWLEDGE AND SKILLS

Strong leadership capability with demonstrated success leading through managers and senior professionals in a complex GMP environment
Proven ability to convert strategy into operational execution plans and to sustain delivery through clear governance, priorities, and accountability
Strong knowledge of global GMP/GDP requirements and commercial packaging and labeling operations in a pharmaceutical environment
Demonstrated experience applying risk-based quality principles to operational decisions, escalation management, and release-related activities
Strong working knowledge of packaging and labeling requirements across the US, EU, and rest of world markets
Demonstrated ability to lead cross-functional teams and influence internal and external stakeholders without direct authority
Strong communication, facilitation, and decision-making skills, with the ability to align teams around clear actions and priorities
Experience developing quality metrics, monitoring operational performance, and driving process improvement
Strong ability to identify organizational gaps, clarify decision ownership, and strengthen operating discipline across multiple levels of the organization
Experience with Operational Excellence tools and methods, including Root Cause Analysis and continuous improvement approaches
Strong judgment, attention to detail, and ability to balance compliance, business continuity, and execution pace

Skills named in this posting

What you'll do

The responsibilities of this position will include, but are not limited to, the following:

Lead operational quality oversight for commercial resupply and lifecycle management of finished goods primary and secondary packaging and labeling activities across US and UK/EU CMOs.
Translate departmental strategy and business priorities into operational quality plans, resource priorities, and execution expectations for the packaging and labeling quality team
Proactively build team capability, an inclusive environment and drive consistent team execution. Provide direct leadership for people managers and/or senior staff, demonstrating understanding of team strengths and development areas and leveraging expertise effectively through performance management, talent development, coaching, and succession planning.
Lead prioritization, decision-making, and coordination across packaging and labeling operational quality activities so that issues are managed at the appropriate level and business results are delivered across the organization
Act as the primary escalation leader for significant packaging and labeling operational quality issues, ensuring timely triage, risk assessment, communication, and appropriate resolution
Lead cross-functional operational forums related to commercial resupply and lifecycle packaging and labeling quality, ensuring clear accountability, decision tracking, follow-through, and alignment across internal stakeholders and CMO partners
Ensure robust procedural oversight of exemption management, QP-related activities, artwork and packaging process change controls, and batch documentation review within the scope of the function
Ensure robust procedural oversight for disposition of commercial primary and secondary packaged goods, CMO oversight and QTA compliance monitoring, including risk-based assessment of changes, investigations, jurisdictional limitations and quality events that may affect release or supply status
Ensure quality processes for commercial resupply and lifecycle packaging and labeling operations are maintained and continuously improved to support compliance, efficiency, business continuity, and risk mitigation across all commercial SM and bio/combo device modalities and product lines.
Monitor, and trend operational quality metrics and KPIs; ensure metrics identify emerging risks, support management review; ensure team is prepared to collate executive slide presentations for each level of quality governance and leadership review (APQR, Ops Review, QMR, GPLB etc.)
Build and maintain effective working relationships with CMO Leadership, Qualified Persons, and other external partner leadership to support compliant and reliable commercial operations partnership
Ensure robust resupply quality input to operational deviation/investigation RCA, CAPA, efficacy checks, product impact assessments, and process support for product complaint investigations related to pack and label operations.
Ensure inspection and audit readiness within the function and provide leadership support for inspections, responses, and follow-up actions as needed
Partner with senior Vertex QA leadership on organization design, operating model effectiveness, and capability-building needs across the packaging and labeling quality organization
Drive clarity of roles, responsibilities, and decision rights across the team to enable appropriate ownership at all levels within the resupply unit as well as across partner interfaces

Pay and benefits

$184,600 – $277,000 a year

Employer provided

How this compares

$184,600 - $277,000

Annual bonus
Annual equity awards
Medical, dental and vision benefits
Generous paid time off
Student loan repayment and educational assistance
401(k)

Where you'll work

Boston, MAHybridOpen in Maps (opens in a new tab)

More jobs in Boston, MA

Working conditions

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

A large group of smiling Vertex interns posed together on an outdoor terrace

From the posting

About Vertex

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex company page · 29 open roles

Equal opportunity, accessibility and legal noticesVertex Pharmaceuticals's statements, word for word

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Job intelligence

The context around this role

Live data · October 13, 2026

Salary intelligence

How the pay compares

This role's midpoint is 10% above the US median for Quality Assurance roles at this level.

This roleEmployer provided

Director roles in Massachusetts19 roles publishing pay

Director roles in the US68 roles publishing pay

Annual base pay
Annual base pay	Low	Median	High
This role	$184,600	—	$277,000
Massachusetts (middle half)	$188,750	$200,000	$254,750
All US (middle half)	$185,375	$210,000	$240,250

This role: Vertex Pharmaceuticals's own published range. Comparisons: the base pay employers published on open Quality Assurance roles at the same level on Regulatory Jobs, October 13, 2026. Nothing is estimated.

Career trajectory

Where this role sits in Quality Assurance

The general path across 642 open Quality Assurance roles on Regulatory Jobs, with the titles they carry most. Not Vertex's own promotion track.

Earlier
Associate & Specialist
Often: Quality Engineer · Intern
$84K median162 open
Earlier
Senior & Principal
Often: Quality Engineer · Senior Quality Engineer
$124K median290 open
One step back
Manager
Often: QA Supervisor · Supplier Quality Manager
$150K median100 open
This role
Director
Often: Associate Director · Associate Director, Quality Assurance
$210K median78 open
Next step
VP & Executive
Often: AVP · Executive Director Quality, Cell & Gene Therapy
$293K median12 open