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New · posted Oct 31

Janux Therapeutics · Biotechnology

Clinical Trial Manager/Senior Clinical Trial Manager (AID)

  • San Diego, CA
  • Hybrid
  • Full-time
  • Manager
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Pay$140K–$178K
ScheduleMon–Fri
LocationSan Diego, CA
LevelManager
FunctionClinical Trial Management
DeadlineOpen until filled

The role

The Senior/Clinical Trial Manager will be responsible for managing and executing operational aspects of assigned clinical trials, from study start-up to close-out, with a focus on autoimmune studies. This individual will be instrumental in managing and overseeing CROs, study vendors, and clinical trial sites, while partnering with key internal stakeholders to ensure clinical trial deliverables are completed on time, within budget, and in accordance with regulatory requirements, GCP guidelines, and internal SOPs. This position reports directly to the Senior Director of Clinical Operations and serves as an integral member of the Clinical Operations team, contributing to the development of trial strategy, executing initiatives, and ensuring the highest standards in operational delivery. This is a great opportunity to make a meaningful impact in a fast-paced, mission-driven biotech environment.

What you need

REQUIRED EDUCATION, EXPERIENCE, SKILLS, AND ABILITIES

  • Bachelor’s degree with at least 5 years (CTM) or 8 years (Sr. CTM) of hands-on clinical trial experience, preferably within a pharmaceutical or biotech environment. A combination of CRO and sponsor-side experience will be considered.
  • Demonstrated experience in complex autoimmune clinical trials, including trial set-up, monitoring, and close-out.
  • Strong working knowledge of ICH/GCP regulations.
  • Proficiency with electronic systems such as eTMF, CTMS, EDC, etc.
  • Ability to work independently with minimal oversight and thrive in a collaborative team environment.
  • Strong critical thinking skills, a sense of urgency, and a proactive problem-solving mindset.
  • Excellent interpersonal, written, and verbal communication skills.
  • Proficiency in MS Office and comfort with technology.
  • Minimal travel required (0 to 5%).

    • Job Type: Full-time

    Skills named in this posting

    What you'll do

    ESSENTIAL FUNCTIONS AND RESPONSIBILITIES

    • Support the successful execution of clinical trials from protocol concept to clinical study report in support of complex autoimmune programs.
    • Prepare and maintain study-related files and documentation to ensure inspection readiness.
    • Organize and lead study and departmental meetings, including minute-taking and document archiving.
    • Coordinate clinical trial equipment, supplies, and cross-functional project activities (e.g., Clinical Data Review Meetings).
    • Ensure team compliance with study-specific training and perform TMF reviews for completeness.
    • Support clinical sites in preparation for audits and inspections.
    • Assist with budget management and day-to-day clinical operations in compliance with SOPs, ICH/GCP, and regulatory requirements.
    • Track subject and site activity/metrics and perform quality checks across study components.
    • Proactively identify and escalate issues related to functional deliverables.
    • Contribute to study set-up activities including protocol/synopsis development, informed consent forms, system configuration (CTMS, IRT), regulatory submissions, and operational documentation.
    • Collaborate with CROs to ensure timely collection and archiving of TMF documents.
    • Coordinate with regulatory affairs on essential document submissions.
    • Support study close-out activities including TMF and drug reconciliation and CSR readiness.
    • Communicate effectively with study team members and work closely with Clinical Trial Managers and/or Asset Leads.
    • Participate in process improvement and quality initiatives related to study execution.
    • Other duties as deemed necessary.

    Pay and benefits

    $140,000 – $178,000 a year

    Employer provided
    How this compares
    • Annual targeted bonus %

    • Annual bonus program

    • Incentive stock option plan

    • 401k plan with flat non-elective employer contribution

    • 100%

      Comprehensive medical insurance with 90-100% employer-paid premiums

    • Dental and vision insurance

    • HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)

    • Unlimited PTO

    • Generous holiday schedule; includes summer and winter company shutdown

    • Relocation assistance

    Where you'll work

    San Diego, CAHybridOpen in Maps (opens in a new tab)

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    Schedule and working conditions

    Days

    Shift5 days a week
    • Monday to Friday

    Work authorization

    • United States (Required)
    Three Janux colleagues laughing together at a conference table

    From the posting

    About Janux

    Work Location

    • Hybrid preferred in San Diego office. Remote permitted upon approval, with ability to travel 25% for meetings or site visits as required.
    Janux company page · 5 open roles
    Equal opportunity, accessibility and legal noticesJanux Therapeutics's statements, word for word

    EQUAL OPPORTUNITY EMPLOYER

    Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.

    Job intelligence

    The context around this role

    Live data · October 31, 2026

    Salary intelligence

    How the pay compares

    This role's midpoint is 2% below the US median for Clinical Trial Management roles at this level.

    This roleEmployer provided

    $140,000 to $178,000 a year

    Manager roles in California10 roles publishing pay

    Middle half $157,875 to $182,125, median $164,000

    Manager roles in the US26 roles publishing pay

    Middle half $150,000 to $175,000, median $162,000
    Annual base pay
    Annual base payLowMedianHigh
    This role$140,000—$178,000
    California$157,875$164,000$182,125
    All US$150,000$162,000$175,000

    This role: Janux Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Trial Management roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.

    Career trajectory

    Where this role sits in Clinical Trial Management

    The general path across 33 open Clinical Trial Management roles on Regulatory Jobs, with the titles they carry most. Not Janux's own promotion track.

    1. Earlier

      Associate & Specialist

      Often: Clinical Trial Assistant

      1 open

    2. One step back

      Senior & Principal

      Often: Senior Clinical Trial Associate · Senior Clinical Trial Leader

      2 open

    3. This role

      Manager

      Often: Senior Clinical Trial Manager · Clinical Trial Manager

      $162K median29 open

    4. Next step

      Director

      Often: Associate Director, Clinical Development Trial Lead

      1 open

    Skills DNA

    What this role leans on

    How many of the posting's 19 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.

    GMP and compliance: 6 linesLab testing and methods: 1 lineDocumentation and SOPs: 9 linesRegulatory submissions: 2 linesQuality systems and risk: 1 lineData and digital systems: 1 lineClinical trial conduct: 9 linesCollaboration and leadership: 7 linesGMPLab testingDocumentationSubmissionsQuality systemsData systemsClinical trialsTeamwork
    • Documentation and SOPs9
    • Clinical trial conduct9
    • Collaboration and leadership7
    • GMP and compliance6
    • Regulatory submissions2
    • Lab testing and methods1
    • Quality systems and risk1
    • Data and digital systems1

    Regulatory intelligence

    The rules behind this role

    Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.

    From Regulatory News

    Company hiring pulse

    Janux on Regulatory Jobs

    5
    Open roles
    5
    Distinct roles
    1
    Locations

    By discipline

    • Clinical4 80%
    • Regulatory1 20%

    By level

    • VP & Executive2 40%
    • Director1 20%
    • Manager1 20%
    See all 5 Janux roles

    More roles at Janux

    Similar Clinical Trial Management roles elsewhere

    Clinical Trial Manager/Senior Clinical Trial Manager (AID) at Janux

    Open until filled. $140K–$178K a year, employer provided.

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