New · posted Oct 15
Cytokinetics · Pharmaceuticals
Senior Manager, Regulatory Operations - Systems
- Radnor, PA
- Hybrid
- Full-time
- Manager
Open until filled
The role
Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
Cytokinetics is seeking a Sr. Manager Regulatory Operations – Systems to support operational management and continuous improvement of Cytokinetics’s Regulatory Information Management systems and processes, with a primary focus on Veeva Vault RIM.
This role will be responsible for assisting with regulatory systems projects/upgrades, supporting day-to-day operational use of the systems, and will be a major contributor in the overall vision of the regulatory systems roadmap.
What you need
Bachelor’s degree in Life Science, Computer Science, or Business, with 5+ years of managing regulatory operations systems or regulatory publishing.
Strong understanding of Veeva RIM, supporting/maintaining regulatory operations systems, and global regulatory submission requirements.
Strong organizational, written, and verbal communication skills.
Analytical and problem-solving skills and ability to identify technical issues requiring escalation.
Previous experience managing regulatory system implementations is a plus.
What you'll do
With oversight from the Associate Director, Regulatory Systems & Training, and in partnership with QA and IT, support and maintain all operational aspects of Cytokinetics’ regulatory systems.
Maintain Vault RIM configuration: Lifecycles, workflows, document types/subtypes/classifications, security profiles, and user roles.
Manage User access requests and training requirements for Regulatory Systems. Provide hands-on training and end-user support as needed
Support the overall end user adoption of new enhancements and processes, leading small to medium initiatives within Regulatory and across other Cytokinetics functions
Coordinate with Veeva Support and Managed Services for advanced issue resolution, enhancement requests, and best-practice guidance.
Collaborate with Regulatory Affairs, Regulatory Operations, Quality, and Clinical teams to align RIM capabilities with business needs.
Support change control processes in partnership with IT/QA for new system releases and enhancements.
Serve as a key contributor to validation activities for regulatory systems
Cross-train with other areas of Regulatory Operations (e.g., Regulatory Project Management, Regulatory Publishing) and provide support, as needed, during periods of peak workload
Pay and benefits
$177,300 – $206,850 a year
Employer providedThe expected salary range for this position based on the primary location of Radnor, PA is $177,300-$206,850. The base pay offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.
Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.
Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.
Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.
Stock options and/or restricted stock units
Health, dental, vision, life and disability insurance
401k with employer match
Learning and wellness stipends
Paid time off
Where you'll work
Radnor, PAHybridOpen in Maps (opens in a new tab)
More jobs in Radnor, PAEqual opportunity, accessibility and legal noticesCytokinetics's statements, word for word
Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.
Here are some ways to check for authenticity:
We do not conduct job interviews through non-standard text messaging applications
We will never request personal information such as banking details until after an official offer has been accepted and verified
We will never request that you purchase equipment or other items when interviewing or hiring
If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at [email protected]
Job intelligence
The context around this role
Live data · October 15, 2026
Salary intelligence
How the pay compares
This role's midpoint is 8% above the US median for Regulatory Operations roles at this level.
This roleEmployer provided
Manager roles in the US8 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $177,300 | — | $206,850 |
| All US (middle half) | $168,125 | $178,250 | $183,750 |
This role: Cytokinetics's own published range. Comparisons: the base pay employers published on open Regulatory Operations roles at the same level on Regulatory Jobs, October 15, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Regulatory Operations
The general path across 34 open Regulatory Operations roles on Regulatory Jobs, with the titles they carry most. Not Cytokinetics's own promotion track.
Career resources on Regulatory Operations
Skills DNA
What this role leans on
How many of the posting's 17 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Collaboration and leadership5
- Data and digital systems4
- Quality systems and risk2
- Lab testing and methods1
- Documentation and SOPs1
- Validation and qualification1
- Regulatory submissions1
Company hiring pulse
Cytokinetics on Regulatory Jobs
- 12
- Open roles
- 11
- Distinct roles
- 2
- Locations
By discipline
- Regulatory6 50%
- Quality4 33%
- Compliance & Safety2 17%
By level
- Director5 42%
- Manager5 42%
- Senior & Principal2 17%
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Senior Manager, Regulatory Operations - Systems at Cytokinetics
Open until filled. $177K–$207K a year, employer provided.