New · posted Nov 1
ICON · Pharmaceuticals
Senior Clinical Research Associate
- Remote, US
- Remote
- Full-time
- Senior & Principal
The role
Senior Clinical Research Associate - Oncology - Knoxville, TN
At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.
As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.
What you need
You are
A graduate with a Bachelor’s degree in Life Sciences or equivalent, or a qualified RN
Eligible to work in United States without visa sponsorship
A clinical research professional with 3+ years of on-site monitoring experience in the pharmaceutical or CRO industry
Experienced monitoring Oncology (i.e. Prostate Cancer, and Lung Cancer) and/or Hematology oncology trials
Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF
A clear communicator, problem-solver, and collaborative team player
Willing and able to travel up to 50% for on-site monitoring visits across southeast region; preference given to candidates residing in TN or KY near major HUB airports to support efficient regional travel
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
What you'll do
What You Will Be Doing
Serve as the primary point of contact between investigational sites and the sponsor
Conduct all types of site visits, including selection, initiation, routine monitoring, and close-out
Ensure site compliance with ICH-GCP, SOPs, and regulations
Maintain up-to-date documentation in CTMS and eTMF systems
Support and track site staff training and maintain compliance records
Monitor patient safety, ensuring timely and accurate AE/SAE/PQC reporting
Support subject recruitment and retention efforts at the site level
Oversee drug accountability and ensure proper storage, return, or destruction
Resolve data queries and drive timely, high-quality data entry
Document site progress and escalate risks or issues to the clinical team
Assist in tracking site budgets and ensuring timely site payments (as applicable)
Collaborate with cross-functional partners including CTAs, LTMs, and CTMs
Pay and benefits
ICON didn't publish pay for this role
See what similar roles pay on Regulatory Jobs, or try the salary calculator.
Rewards & Benefits
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Equal opportunity, accessibility and legal noticesICON's statements, word for word
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Job intelligence
The context around this role
Live data · November 3, 2026
Salary intelligence
How the pay compares
Senior & Principal roles in the US51 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| All US (middle half) | $120,250 | $124,500 | $130,500 |
Comparisons: the base pay employers published on open Clinical Research roles at the same level on Regulatory Jobs, November 3, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Research
The general path across 210 open Clinical Research roles on Regulatory Jobs, with the titles they carry most. Not ICON's own promotion track.
Career resources on Clinical Research
Skills DNA
What this role leans on
How many of the posting's 23 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct6
- Collaboration and leadership5
- Documentation and SOPs4
- GMP and compliance3
- Lab testing and methods1
- Investigations and CAPA1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
ICON on Regulatory Jobs
- 122
- Open roles
- 61
- Distinct roles
- 32
- Locations
By discipline
- Clinical112 92%
- Quality7 6%
- Regulatory3 2%
By level
- Associate & Specialist54 44%
- Senior & Principal49 40%
- Manager16 13%
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Senior Clinical Research Associate at ICON
Open until filled.