New · posted Nov 1
Parexel · Pharmaceuticals
Senior Clinical Database Programmer - eCOA
- Remote, US
- Remote
- Full-time
- Senior & Principal
The role
We are seeking a Principal Database Programmer (eCOA Study Builder /Designer) specializing in electronic Clinical Outcome Assessment (eCOA) solutions to join our team in a remote capacity, based in the any location in the continental US. As a Principal Database Programmer (eCOA Study Builder/ Designer), you will provide technical expertise for the design, configuration, testing, deployment, and maintenance of eCOA solutions used in clinical trials. This position plays a key role in study execution, regulatory compliance, and clinical data accuracy. You will translate protocols, assessment schedules, and licensed instrument requirements into compliant participant, caregiver, and clinician facing questionnaires, schedules, and workflows. You will collaborate with sponsors and cross-functional teams, follow industry-standard processes, and contribute to eCOA study delivery from design through closeout. Responsibilities include configuring and testing eCOA studies in approved platforms and supporting their integration with Electronic Data Capture (EDC) systems, with opportunities to deepen your expertise and influence study outcomes.
You will join a fast-paced, growth-oriented environment focused on making a meaningful impact through building eCOA studies that generate reliable, high-quality data, supporting multiple projects at once, and sharing technical expertise with project teams. With diverse teams and continuous learning opportunities, the Principal Database Programmer (eCOA Study Builder / Designer) can explore career paths and expand skills across clinical research.
What you need
Required Qualifications
- Bachelor's degree in life sciences, computer science, health informatics, clinical research, or a related discipline
- Proven experience with eCOA, ePRO, or eDiary
- Strong clinical research industry experience within a CRO or pharmaceutical setting
- Experience with EDC systems and an understanding of eCOA-to-EDC configuration dependencies and data flow
- Knowledge of questionnaire design, schedules, branching logic, reminders, notifications, translations, version management, and participant workflows
- Knowledge of SOPs, Work Instructions, system life-cycle methodologies, ICH-GCP, 21 CFR Part 11, and other applicable local and international regulatory requirements
- Experience with technical quality control, UAT, defect management, change control, and validated clinical systems
- Experience supporting global studies, sponsors, and cross-functional project teams
- Strong communication, organization, and problem-solving skills, including root-cause analysis, risk identification, and decision-making in ambiguous situations
- Proficient presentation and system-demonstration skills
- Written and oral fluency in English
Candidate Profile
You'll thrive in this role if you bring:
- Strengths in questionnaire design, eCOA study configuration, and technical quality control
- Experience working in clinical research, healthcare, or a regulated environment
- The ability to collaborate across global, cross-functional teams and communicate technical design decisions clearly to technical and non-technical audiences
- A patient-focused mindset and strong attention to detail
- Comfort working with eCOA platforms such as Medidata Designer eCOA, EDC systems such as Medidata Rave, and validated clinical systems
Preferred Qualificationsnice to have
- Hands-on experience configuring an eCOA platform such as Medidata Designer eCOA, or comparable study-design technology
- Experience with Medidata Rave EDC
What you'll do
- Design, set up, maintain, revise, and close out eCOA studies by interpreting protocols, schedules of assessments, eCOA specifications, and licensed instrument requirements
- Configure questionnaires, screens, field properties, code lists, schedules, branching logic, rules, reminders, alerts, notifications, and study settings in the approved eCOA platform, applying established naming conventions and build standards
- Coordinate the initial eCOA configuration and controlled push to EDC, maintaining alignment among the eCOA configuration, EDC draft, and applicable CRF versions
- Assess and implement approved protocol amendments, production revisions, translations, and study maintenance changes while protecting data integrity and traceability
- Perform technical quality control of eCOA configurations against approved specifications and support User Acceptance Testing (UAT), including test evidence, defect triage, and resolution
- Coordinate deployment readiness and support post-production troubleshooting and controlled implementation of approved corrections
- Collaborate with Clinical Database Programming, Data Management, eCOA Clinical Data Analysis, COA Science, and Clinical Operations to finalize eCOA requirements and resolve design issues
- Lead or participate in design and build meetings, communicate configuration status, identify risks and dependencies, and manage scope, timeline, and resourcing changes across multiple projects
- Serve as a technical contact for sponsors and vendors on eCOA design, specification, testing, and deployment topics, as assigned
- Create and maintain eCOA specifications, configuration records, test evidence, and other study artifacts in accordance with SOPs, Work Instructions, ICH-GCP, and applicable regulatory requirements
- Provide role-relevant training, coaching, and technical guidance to project teams and less-experienced study designers, and contribute to standards, reusable libraries, and continuous improvement
Pay and benefits
$110,000 – $140,000 a year
Employer providedBenefits and Compensation
- Health, Vision & Dental Insurance
- Tuition Reimbursement
- Vacation/Holiday/Sick Time
- Flexible Spending & Health Savings Accounts
- Work/Life Balance
- 401(k) with Company match
- Pet Insurance
For a complete list of benefits, please visit www.parexel.com/us-benefits.
The potential base pay range for this role is $110,000 to $140,000 USD yearly salary. The actual salary offered may vary within this range based on several factors, including the position and level offered, skills, education, training, experience, professional achievements, and location.
Some roles may also be eligible for additional incentives, bonuses, or other compensation programs. Our Talent Acquisition team will provide details on applicable bonus plans or incentive structures for eligible positions.
We offer a comprehensive benefits package to eligible employees, which includes paid time off, a 401(k) match, life insurance, health insurance, and additional benefit offerings in accordance with the terms of our applicable plans.
If this job doesn't sound like the next step in your career, but perhaps you know of someone who'd be a perfect fit, send them the link to apply!
We believe in flexibility, growth, and creating space for people to do their best work. Join us and be part of a team where your contributions help shape the future of clinical research.
Health, vision & dental insurance
401(k) with company match
Tuition reimbursement
Vacation/holiday/sick time
Flexible Spending & Health Savings Accounts
Pet insurance
From the posting
About Parexel
When our values align, there's no limit to what we can achieve.
At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.
Each of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.
Parexel is a leading global clinical development partner delivering insights-driven clinical and consulting solutions to the life sciences industry. With 22,000+ employees worldwide, we partner with biopharmaceutical companies and research sites to design and deliver patient-focused clinical trials that broaden access and make research a care option for anyone, anywhere.
We work with focus, agility, and shared purpose, moving with urgency to address patient needs and accelerate the delivery of new therapies. We embrace bold thinking, adapt quickly to change, and continually raise the bar for the speed and quality of clinical research. We are expanding our team and seeking talented individuals to help drive industry-leading innovation, With Heart®.
Equal opportunity, accessibility and legal noticesParexel's statements, word for word
EEO Disclaimer
Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
Job intelligence
The context around this role
Live data · November 3, 2026
Salary intelligence
How the pay compares
This role's midpoint is 12% below the US median for Clinical Data Management roles at this level.
This roleEmployer provided
Senior & Principal roles in the US15 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $110,000 | — | $140,000 |
| All US (middle half) | $128,250 | $142,500 | $155,250 |
This role: Parexel's own published range. Comparisons: the base pay employers published on open Clinical Data Management roles at the same level on Regulatory Jobs, November 3, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Data Management
The general path across 55 open Clinical Data Management roles on Regulatory Jobs, with the titles they carry most. Not Parexel's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 32 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct11
- Collaboration and leadership8
- Lab testing and methods6
- Data and digital systems6
- GMP and compliance3
- Documentation and SOPs2
- Validation and qualification2
- Quality systems and risk2
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- FDAFDA data integrity guidance(official source, opens in a new tab)Data Integrity and Compliance With Drug CGMP: Questions and Answers
- ICHICH quality guidelines(official source, opens in a new tab)Q1 stability, Q2(R2) analytical validation, Q7, Q9 risk management, Q10 quality systems
- ICHICH E6 good clinical practice(official source, opens in a new tab)The international standard for the conduct of clinical trials
Company hiring pulse
Parexel on Regulatory Jobs
- 47
- Open roles
- 46
- Distinct roles
- 6
- Locations
By discipline
- Clinical28 60%
- Regulatory18 38%
- Quality1 2%
By level
- Senior & Principal31 66%
- Manager10 21%
- Associate & Specialist5 11%
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Senior Clinical Database Programmer - eCOA at Parexel
Open until filled. $110K–$140K a year, employer provided.