New · posted Nov 1
Pfizer · Pharmaceuticals
Principal Validation Engineer
- Andover, MA
- Hybrid
- Full-time
- Senior & Principal
The role
Use Your Power for Purpose
The Principal Validation Engineer under Andover Site Technical Services (STS) is the principal owner of the Pfizer (PGS) Andover site validation program and master plan. The incumbent is responsible for delivering overall site validation program effectiveness and compliance in partnership with validation program owners across Andover site functions and the Pfizer network
What You Will Achieve
In this role, you will:
Establish and maintain overall Andover site validation philosophy and master plan in partnership with local validation program owners, technical subject matter experts, and relevant Pfizer global/network/site quality system principals applicable to biologics drug substance/drug substance intermediate production, testing, storage, and transport
Operate PMO for Validation Program Lifecycle Projects
Establish and maintain site governances necessary to interpret validation philosophies and polices, implement and improve uniform validation practices and approaches, as well as to measure and maintain site validation program health
Maintain STS departmental infrastructure, and provide planning support for third party services utilized in validation and other technical services; oversee third party service provider service level and quality of service
Program owner and expert for select technical/validation disciplines
STS capital project portfolio and expense planning
Lead site validation planning and management of validation activities for large capital or complex asset lifecycle projects
What you need
Here Is What You Need (Minimum Requirements)
BA/BS degree in Science or Engineering with 6+ years of experience or MBA/MS with 5+ years of experience or PhD/JD with 1+ year of experience or MD/DVM with any years of relevant experience
Experience in pharmaceutical, biopharmaceutical or biotechnology industry
Experience or broad knowledge in biopharmaceutical development, manufacturing, and lifecycle management
Experience in project management and leading complex projects
Effective written and verbal communication skills
Strong interpersonal skills and the ability to work collaboratively in a team environment across various business functions
Physical / Mental requirements
Ability to perform mathematical calculations, scientific computation, complex data analysis, verbal communication, written communication
Non-Standard work schedule, travel or environment requirements
Occasional domestic and international travels
Occasional off-hour support to address time-sensitive production and business-related issues
Bonus Points If You Have (Preferred Requirements)nice to have
Experience developing philosophies/approaches for or managing validation programs applicable to the manufacture of biopharmaceutical drug substance, drug product, or medical device
Active participation in industrial/professional organization focused on advancing biopharmaceutical development, manufacturing, regulatory practices
Demonstrated ability to lead or build teams for complex technical projects involving risk management
Demonstrated leadership in a matrix organization
Pay and benefits
$124,400 – $207,400 a year
Employer providedOther job details
Last day to apply: July 17th, 2026
Work Location Assignment: Hybrid
The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
401(k) with Pfizer matching contributions
Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Annual bonus and long-term incentive eligibility
Where you'll work
Andover, MAHybridOpen in Maps (opens in a new tab)
More jobs in Andover, MA
From the posting
About Pfizer
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Equal opportunity, accessibility and legal noticesPfizer's statements, word for word
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Engineering
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 37% above the US median for Validation & CQV roles at this level.
This roleEmployer provided
Senior & Principal roles in Massachusetts9 roles publishing pay
Senior & Principal roles in the US55 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $124,400 | — | $207,400 |
| Massachusetts (middle half) | $115,500 | $123,000 | $138,500 |
| All US (middle half) | $110,750 | $121,500 | $133,500 |
This role: Pfizer's own published range. Comparisons: the base pay employers published on open Validation & CQV roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Validation & CQV
The general path across 127 open Validation & CQV roles on Regulatory Jobs, with the titles they carry most. Not Pfizer's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 22 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Validation and qualification8
- Collaboration and leadership6
- Quality systems and risk2
- GMP and compliance1
- Lab testing and methods1
Company hiring pulse
Pfizer on Regulatory Jobs
- 14
- Open roles
- 14
- Distinct roles
- 8
- Locations
By discipline
- Clinical7 50%
- Quality6 43%
- Regulatory1 7%
By level
- Director5 36%
- Manager4 29%
- Senior & Principal3 21%
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Principal Validation Engineer at Pfizer
Applications close November 14. $124K–$207K a year, employer provided.