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New · posted Oct 31

Relay Therapeutics · Biotechnology

Medical Director/Senior Medical Director, Patient Safety & Risk Management

  • Cambridge, MA
  • On-site
  • Full-time
  • Director
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EmploymentFull-time
DeadlineOpen until filled

The role

The Medical Director, Patient Safety & Risk Management at Relay Therapeutics will serve as the Global Medical Safety Lead (GSL) and provides strategic and medical leadership for the safety surveillance and risk management of Relay Therapeutic assigned products throughout the product lifecycle. This role is responsible for the evaluation, interpretation, and communication of safety information; signal detection and management; benefit-risk assessment; and development of risk minimization strategies to ensure patient safety and regulatory compliance. In addition, the GSL will support the medical review of individual case safety reports and safety surveillance activities as needed for assigned Relay Therapeutic products. The GSL will lead the cross functional Safety Management Team in the evaluation  of safety signals and implementation of risk minimization activities for Relay Therapeutic products.

We are seeking  a safety physician, who thrives in a dynamic, agile biotech environment. Reporting to the Executive Director, Patient Safety & Risk Management, this individual serve as a key collaborator and leader in cross functional clinical program teams, including Clinical Development, Clinical Operations, Biostats, Data Management and Regulatory Affairs. The successful candidate will play a critical role in advancing the development of transformative therapies by providing medical safety expertise.

What you need

What you'll do

Your Role

  • Direct the planning, preparation, writing and review of safety aggregate reports, including DSUR.
  • Train/collaborate and support qualified PSRM staff on medical review, safety surveillance activities and authoring of aggregate reports.
  • Provide benefit-risk assessment on potential safety signal or in safety documents/reports and leads product benefit-risk assessment discussions at safety management meetings.
  • Lead cross functional safety management team meetings and escalate safety issues including preparing and presenting of safety issue and recommendation to the executive decision-making body.
  • Contribute to the development of Investigator Brochures, Protocols, Subject Informed Consent, statistical analysis plans, integrated safety summary, RMP/REMS, and other study related documents
  • Support and collaborate with cross functional teams on safety related activities including providing responses to safety related queries from regulatory authorities and IRB/EC.
  • Ensure compliance with regulatory guidelines and internal processes and procedures, to be inspection ready and serve as SME in audits and inspections.
  • Serve as back-up medical review/sponsor approval of ICSRs and ensure appropriate medical evaluation of individual case safety reports and emerging safety trends.

Pay

$201,000 – $351,000 a year

Employer provided
How this compares

Your Background

  • MD, DO or medical degree from an accredited medical school and completion of an accredited medical or surgical residency or clinical experience in either academic setting or private practice
  • A minimum of drug safety experience 7-10 years in the pharmaceutical industry
  • Experience leading cross functional teams and/or projects
  • Expertise in analyzing and presenting complex medical-scientific data from broad range of sources required
  • Experience providing medical leadership and strategic review of aggregate safety reports (DSUR, PBRER/PSUR) is required
  • Knowledge of global risk management planning including RMPs, REMS (Risk Evaluation and Mitigation strategies) and risk minimization strategies required
  • Expertise in global regulations governing safety surveillance and risk management
  • Prior NDA filing (ISS drafting and review) experience strongly preferred

Estimated Salary Range: [$201,000 - $351,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

Where you'll work

Cambridge, MAOn-siteOpen in Maps (opens in a new tab)

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Ten smiling Relay Therapeutics colleagues on a Cambridge sidewalk holding letters that spell RELAY

From the posting

About Relay Therapeutics

Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.

Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Relay Therapeutics company page · 4 open roles

Job intelligence

The context around this role

Live data · October 31, 2026

Salary intelligence

How the pay compares

This role's midpoint is 6% above the US median for Clinical Safety & Pharmacovigilance roles at this level.

This roleEmployer provided

$201,000 to $351,000 a year

Director roles in Massachusetts24 roles publishing pay

Middle half $217,500 to $281,000, median $229,000

Director roles in the US69 roles publishing pay

Middle half $213,500 to $281,000, median $260,000
Annual base pay
Annual base payLowMedianHigh
This role$201,000—$351,000
Massachusetts$217,500$229,000$281,000
All US$213,500$260,000$281,000

This role: Relay Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Safety & Pharmacovigilance roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.

Career trajectory

Where this role sits in Clinical Safety & Pharmacovigilance

The general path across 113 open Clinical Safety & Pharmacovigilance roles on Regulatory Jobs, with the titles they carry most. Not Relay Therapeutics's own promotion track.

  1. Earlier

    Associate & Specialist

    Often: Associate, Pharmacovigilance Operations/Drug Safety · Clinical Sciences Partnership COE Coordinator

  2. Earlier

    Senior & Principal

    Often: Senior Safety Scientist · Clinical FSP Quality Manager

    $186K median11 open
  3. One step back

    Manager

    Often: Senior Manager, Clinical Quality Assurance · Clinical FSP Quality Manager

    $170K median15 open
  4. This role

    Director

    Often: Director · Senior Medical Director

    $260K median70 open
  5. Next step

    VP & Executive

    Often: Head of Multiple Myeloma & AML, Oncology · Head of Patient-Facing Quality Assurance

    $347K median12 open

Skills DNA

What this role leans on

How many of the posting's 10 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.

GMP and compliance: 2 linesLab testing and methods: 1 lineDocumentation and SOPs: 7 linesInvestigations and CAPA: 1 lineQuality systems and risk: 3 linesData and digital systems: 1 lineClinical trial conduct: 3 linesCollaboration and leadership: 6 linesGMPLab testingDocumentationInvestigationsQuality systemsData systemsClinical trialsTeamwork
  • Documentation and SOPs7
  • Collaboration and leadership6
  • Quality systems and risk3
  • Clinical trial conduct3
  • GMP and compliance2
  • Lab testing and methods1
  • Investigations and CAPA1
  • Data and digital systems1

Company hiring pulse

Relay Therapeutics on Regulatory Jobs

4
Open roles
4
Distinct roles
1
Locations

By discipline

  • Regulatory2 50%
  • Clinical2 50%

By level

  • Director3 75%
  • Senior & Principal1 25%
See all 4 Relay Therapeutics roles

More roles at Relay Therapeutics

Similar Clinical Safety & Pharmacovigilance roles elsewhere

Medical Director/Senior Medical Director, Patient Safety & Risk Management at Relay Therapeutics

Open until filled. $201K–$351K a year, employer provided.

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