New · posted Oct 31
HeartFlow · Medical Devices
Clinical Trial Manager - Investigator Initiated Studies
- Remote, US
- Remote
- Full-time
- Manager
The role
Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.
Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 750,000 patients worldwide.
The Clinical Trial Manager (CTM) - Investigator Initiated Studies is responsible for the oversight and management of all clinical operational activities for investigator initiated studies. The CTM will interact well with the HeartFlow Clinical Research staff and collaborate effectively with HeartFlow onsite and field staff, clinical research coordinators, principal investigators, and vendors to aid in ensuring clinical studies meet or exceed timelines and maintain high quality standards. The CTM will have demonstrated experience with clinical research study execution, exceptional organizational skills, excellent attention to detail, and will be comfortable working in a fast-paced start-up culture.
What you need
Educational Requirements & Work Experience
- Bachelor’s degree in science or health related field
- Demonstrated 5 years minimum relevant experience required
- Experience managing investigator initiated studies a plus
- Experience in cardiovascular medical device clinical research a plus
Heartflow has become aware of a fraud where unknown entities are posing as Heartflow recruiters in an attempt to obtain personal information from individuals as part of our application or job offer process. Before providing any personal information to outside parties, please verify the following: A) all legitimate Heartflow recruiter email addresses end with “@heartflow.com” and B) the position described is found on our careers site at www.heartflow.com/about/careers/.
Skills Needed
- Ability to work in a smaller team environment with a willing, all hands-on deck attitude.
- Ability to manage multiple tasks and be comfortable working in an environment with shifting priorities.
- High attention to detail, accuracy, and quality and able to effectively prioritize multiple projects.
- Knowledge of ICH Guidelines, US FDA, and European clinical trial requirements and regulations
- Excellent written and oral English communication skills required.
- Proficiency in computer programs and specifically in Microsoft office tools including Word, Excel and PowerPoint
What you'll do
- Participates in clinical research activities including management of clinical study sites, management of study documentation, vendor management, and completion of project management tasks.
- Develops clinical trial timelines, enrollment projections, and instructional materials in support of trial execution, including project, communication, monitoring, recruitment, risk mitigation, and contingency plans.
- Participates in and leads process improvement activities within the department and cross functionally, including SOP development.
- Conducts study start-up activities including leading study kick off meetings, contract management, and site onboarding and training.
- Reviews site regulatory documents (informed consents, IRB approvals, research agreements) as needed to ensure compliance with study requirements and GCPs.
- Maintains effective working relationships with investigators/investigational site research coordinators, and vendors including core labs and data management.
- Track internal and external project deliverables to ensure they remain within the timeline and budget.
- Perform other duties as required for successfully completing studies, as necessary.
Pay and benefits
$90,000 – $130,000 a year
Employer providedA reasonable estimate of the base salary compensation range is $90,000 to $130,000 and cash bonus.
Cash bonus
Equal opportunity, accessibility and legal noticesHeartFlow's statements, word for word
Heartflow is an Equal Opportunity Employer. We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination.
Positions posted for Heartflow are not intended for or open to third party recruiters / agencies. Submission of any unsolicited resumes for these positions will be considered to be free referrals.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 32% below the US median for Clinical Trial Management roles at this level.
This roleEmployer provided
Manager roles in the US26 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $90,000 | — | $130,000 |
| All US (middle half) | $150,000 | $162,000 | $175,000 |
This role: HeartFlow's own published range. Comparisons: the base pay employers published on open Clinical Trial Management roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Trial Management
The general path across 33 open Clinical Trial Management roles on Regulatory Jobs, with the titles they carry most. Not HeartFlow's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 22 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct8
- Collaboration and leadership7
- Documentation and SOPs3
- Investigations and CAPA3
- GMP and compliance2
- Data and digital systems2
- Lab testing and methods1
- Quality systems and risk1
Company hiring pulse
HeartFlow on Regulatory Jobs
- 7
- Open roles
- 7
- Distinct roles
- 2
- Locations
By discipline
- Quality3 43%
- Regulatory2 29%
- Clinical2 29%
By level
- Senior & Principal4 57%
- Manager2 29%
- Director1 14%
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Clinical Trial Manager - Investigator Initiated Studies at HeartFlow
Open until filled. $90K–$130K a year, employer provided.