

New · posted Oct 31
Rapport Therapeutics · Biotechnology
Clinical Systems Manager, Clinical Data Management
- Boston, MA
- Hybrid
- Full-time
- Manager
The role
When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!
Your impact
As Clinical Systems Manager you will oversee the implementation, maintenance, optimization, and security of clinical information systems (such as EDC, Data Warehousing and Reporting Tools, IRT, or eCOA) to ensure they support safe, efficient, and compliant clinical research.
Your day-to-day
- System Administration: Manage the deployment, daily operations, upgrades, and configuration of clinical platforms.
- Cross-Functional Liaison: Serve as the primary bridge between clinical end-users (doctors, nurses, researchers) and IT or software development vendors.
- Integration & Data Flow: Oversee system interfaces (such as HL7/FHIR or lab/radiology connections) to ensure data moves accurately between platforms.
- Compliance & Validation: Maintain adherence to regulatory standards like HIPAA, GCP, 21 CFR Part 11, and data privacy rules.
- User Training & Support: Coordinate testing, write Standard Operating Procedures (SOPs), and guide staff on proper system usage.
- Vendor & Project Management: Oversee third-party software providers, track project milestones, and manage system changes.
- Serve as a trusted business partner across Data Management, Biostatistics, Programming, Clinical Operations, Finance, and Clinical Development, fostering cross-functional collaboration and continuous improvement.
Must-Haves
- Bachelor's degree in Computer Science, Information Systems, Nursing, Life Sciences, or a related field.
- 4 to 7 years of combined experience in healthcare, clinical development, or IT data management, including 2+ years in a leadership or system ownership role.
- Proficiency with Electronic Health Record (EHR) systems, database structures (SQL), SAS, cloud environments (AWS/GCP), and data integration standards. CDASH, SDTM, data quality standards and submission requirements
- Strong analytical, organizational, and problem-solving skills with attention to detail.
- Excellent communication and leadership skills with the ability to influence across functions and levels.
What makes Rapport special
- Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.
- We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
- Your perspective matters. Stick your neck out, share your ideas – we work as a team.
- We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.
- Leadership that CARES – about you, your growth + development.
- We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
- Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!
- You get to be YOU! Show up as you are and make every day count.
What you need
Skills named in this posting
Pay and benefits
$120,000 – $145,000 a year
Employer providedWe get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this? We tell you about our hiring range now - we expect the hiring range for the role to be $120,000 to $145,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.
Unlimited PTO
Lifestyle spending account
Commuting reimbursement
Hybrid work schedule
Where you'll work
Boston, MAHybridOpen in Maps (opens in a new tab)
More jobs in Boston, MASchedule and working conditions
Days
Hybrid Work Environment
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
CCPA disclosure notice can be found here.
Equal opportunity, accessibility and legal noticesRapport Therapeutics's statements, word for word
Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
Job intelligence
The context around this role
Live data · October 31, 2026
Salary intelligence
How the pay compares
This role's midpoint is 27% below the US median for Clinical Data Management roles at this level.
This roleEmployer provided
Manager roles in the US11 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $120,000 | — | $145,000 |
| All US (middle half) | $164,500 | $181,000 | $181,000 |
This role: Rapport Therapeutics's own published range. Comparisons: the base pay employers published on open Clinical Data Management roles at the same level on Regulatory Jobs, October 31, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Data Management
The general path across 29 open Clinical Data Management roles on Regulatory Jobs, with the titles they carry most. Not Rapport Therapeutics's own promotion track.
Skills DNA
What this role leans on
How many of the posting's 24 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Data and digital systems9
- Collaboration and leadership9
- Clinical trial conduct4
- GMP and compliance2
- Lab testing and methods2
- Documentation and SOPs2
- Validation and qualification1
- Regulatory submissions1
- Quality systems and risk1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
Rapport Therapeutics on Regulatory Jobs
- 8
- Open roles
- 7
- Distinct roles
- 1
- Locations
By discipline
- Clinical7 88%
- Regulatory1 13%
By level
- Director3 38%
- Manager2 25%
- Senior & Principal2 25%
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Clinical Systems Manager, Clinical Data Management at Rapport Therapeutics
Open until filled. $120K–$145K a year, employer provided.

