

New · posted Nov 1
ICON · Pharmaceuticals
Clinical Research Associate II
- Chicago, IL
- On-site
- Full-time
- Associate & Specialist
The role
Clinical Research Associate - Cross Therapeutic - Chicago
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
What you need
You are
A graduate with a Bachelor’s degree in Life Sciences or equivalent, or a qualified RN
Eligible to work in United States without visa sponsorship
A clinical research professional with 2+ years of on-site monitoring experience in the pharmaceutical or CRO industry
Experienced monitoring across multiple therapeutic areas
Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF
A clear communicator, problem-solver, and collaborative team player
Willing and able to travel up to 60% - 75% for on-site monitoring visits across Midwest region; preference given to candidates residing in Chicago near major HUB airports to support efficient regional travel
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
What you'll do
What You Will Be Doing
Serve as the primary point of contact between investigational sites and the sponsor
Conduct all types of site visits, including selection, initiation, routine monitoring, and close-out
Ensure site compliance with ICH-GCP, SOPs, and regulations
Maintain up-to-date documentation in CTMS and eTMF systems
Support and track site staff training and maintain compliance records
Monitor patient safety, ensuring timely and accurate AE/SAE/PQC reporting
Support subject recruitment and retention efforts at the site level
Oversee drug accountability and ensure proper storage, return, or destruction
Resolve data queries and drive timely, high-quality data entry
Document site progress and escalate risks or issues to the clinical team
Assist in tracking site budgets and ensuring timely site payments (as applicable)
Collaborate with cross-functional partners including CTAs, LTMs, and CTMs
Pay and benefits
$91,336 – $114,170 a year
Employer provided$91,336.00-$114,170.00
Are you a current ICON Employee? Please click here to apply
Rewards & Benefits
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Where you'll work
Chicago, ILOn-siteOpen in Maps (opens in a new tab)
More jobs in Chicago, ILEqual opportunity, accessibility and legal noticesICON's statements, word for word
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Job intelligence
The context around this role
Live data · November 1, 2026
Salary intelligence
How the pay compares
This role's midpoint is 7% below the US median for Clinical Research roles at this level.
This roleEmployer provided
Associate & Specialist roles in the US56 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $91,336 | — | $114,170 |
| All US (middle half) | $80,000 | $110,000 | $127,875 |
This role: ICON's own published range. Comparisons: the base pay employers published on open Clinical Research roles at the same level on Regulatory Jobs, November 1, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Research
The general path across 193 open Clinical Research roles on Regulatory Jobs, with the titles they carry most. Not ICON's own promotion track.
Career resources on Clinical Research
Skills DNA
What this role leans on
How many of the posting's 23 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct7
- Collaboration and leadership5
- Documentation and SOPs4
- GMP and compliance3
- Investigations and CAPA1
- Quality systems and risk1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
ICON on Regulatory Jobs
- 106
- Open roles
- 56
- Distinct roles
- 30
- Locations
By discipline
- Clinical96 91%
- Quality7 7%
- Regulatory3 3%
By level
- Senior & Principal45 42%
- Associate & Specialist43 41%
- Manager15 14%
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Clinical Research Associate II at ICON
Open until filled. $91K–$114K a year, employer provided.

