New · posted Nov 5
ICON · Pharmaceuticals
Clinical Research Associate 3
- Remote, US
- Remote
- Full-time
- Senior & Principal
The role
Senior Clinical Research Associate
At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.
As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.
As a Senior CRA at ICON Plc, you will oversee and manage clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards.
What you need
You will have a strong foundation in clinical trial monitoring, with the experience to work independently and guide others.
Required qualifications and experience:
- Bachelor's degree in a relevant scientific discipline or healthcare-related field
- Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.
- Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.
- Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.
- Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.
- Willingness to travel as required (approximately 60%)
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
What you'll do
You will lead on clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement.
Key responsibilities include:
- Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.
- Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.
- Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.
- Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.
- Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.
Pay and benefits
ICON didn't publish pay for this role
See what similar roles pay on Regulatory Jobs, or try the salary calculator.
Rewards & Benefits
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Equal opportunity, accessibility and legal noticesICON's statements, word for word
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Job intelligence
The context around this role
Live data · November 5, 2026
Salary intelligence
How the pay compares
Senior & Principal roles in Pennsylvania6 roles publishing pay
Senior & Principal roles in the US58 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| Pennsylvania (middle half) | $124,500 | $124,500 | $124,500 |
| All US (middle half) | $111,750 | $124,500 | $127,375 |
Comparisons: the base pay employers published on open Clinical Research roles at the same level on Regulatory Jobs, November 5, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Clinical Research
The general path across 226 open Clinical Research roles on Regulatory Jobs, with the titles they carry most. Not ICON's own promotion track.
Career resources on Clinical Research
Skills DNA
What this role leans on
How many of the posting's 18 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Clinical trial conduct8
- Collaboration and leadership6
- GMP and compliance2
- Lab testing and methods1
- Quality systems and risk1
- Data and digital systems1
Regulatory intelligence
The rules, regulations and standards behind this role
The regulations, guidance and standards that govern Clinical Research work in pharmaceuticals, led by the one this posting names, each linked to the agency or standards body that publishes it.
- ICHICH E6(R3) good clinical practice(official source, opens in a new tab)The international standard for the design, conduct and reporting of clinical trialsNamed in the posting
- FDA21 CFR Part 312(official source, opens in a new tab)Investigational New Drug applications and sponsor duties in drug trials
- FDA21 CFR Part 50(official source, opens in a new tab)Protection of human subjects: informed consent in FDA-regulated trials
- FDA21 CFR Part 56(official source, opens in a new tab)Institutional review boards for FDA-regulated clinical investigations
- EUEU Clinical Trials Regulation 536/2014(official source, opens in a new tab)How clinical trials of medicines are authorized and run in the EU, through CTIS
- ICHICH E8(R1)(official source, opens in a new tab)General considerations for clinical studies and quality by design in trials
- HHS45 CFR Part 46 (Common Rule)(official source, opens in a new tab)The federal policy for the protection of human research subjects
- NIH42 CFR Part 11(official source, opens in a new tab)Clinical trial registration and results reporting on ClinicalTrials.gov
- FDAFDA Bioresearch Monitoring (BIMO)(official source, opens in a new tab)FDA inspections of clinical investigators, sponsors, IRBs and GLP labs
- FDA21 CFR Part 11(official source, opens in a new tab)FDA rules for electronic records and electronic signatures
- HHSHIPAA Privacy Rule(official source, opens in a new tab)Federal protections for individually identifiable health information
- EUGDPR (Regulation 2016/679)(official source, opens in a new tab)The EU General Data Protection Regulation for personal data, including health data
- ICHICH E9 and E9(R1)(official source, opens in a new tab)Statistical principles for clinical trials and estimands
- FDA21 CFR 314.80 and 600.80(official source, opens in a new tab)Postmarketing reporting of adverse drug and biologic experiences
- ICHICH E2A to E2F(official source, opens in a new tab)Clinical safety data management, expedited reporting and periodic safety reports
- ICHMedDRA(official source, opens in a new tab)The ICH medical terminology for coding adverse events and medical history
Company hiring pulse
ICON on Regulatory Jobs
- 140
- Open roles
- 65
- Distinct roles
- 32
- Locations
By discipline
- Clinical129 92%
- Quality7 5%
- Regulatory4 3%
By level
- Associate & Specialist59 42%
- Senior & Principal58 41%
- Manager18 13%
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Clinical Research Associate 3 at ICON
Open until filled.