

Spyre Therapeutics, Inc.
- Biotechnology
- Waltham, MA
- 102 employees
We are committed to transforming the lives of patients and caregivers through our mission to develop improved treatment options for immune-mediated diseases.
Open roles at Spyre
Live · October 12, 2026
- Openings
- 2
- Distinct roles
- 2
- Locations
- 1
By discipline
By level
Top locations
- Remote, US2100%
As of October 12, 2026, Spyre has 2 regulatory, quality and compliance openings on Regulatory Jobs across 1 location, led by Remote, US (2). By discipline: 2 regulatory; by level, 2 manager.
2 roles
Senior Manager, Regulatory Affairs
Remote, USIndustry: BiotechnologyFull-timeSalary: $160K–$176K
Regulatory AffairsManagerSenior Manager, Regulatory Affairs CMC
Remote, USIndustry: BiotechnologyFull-timeSalary: $150K–$176K
Regulatory CMCManager
Where they're hiring
Open roles in 1 location, busiest first.
Remote, US
2 open roles

Life at Spyre
About Spyre
Spyre's regulatory team takes its extended half-life antibodies through global clinical development, from study start-up to its global Phase 3 program, across inflammatory bowel disease and rheumatic diseases.
The work spans clinical trial applications to the FDA, EMA and other health authorities, CRO oversight, health authority interactions and regulatory CMC, in a remote team that meets in person often. Spyre has 102 employees and is headquartered in Waltham, Massachusetts.
- Headquarters
Waltham, MA
- Industry
Biotechnology
- Employees
102
Figures: Spyre 2025 Form 10-K
2 regulatory and quality roles open at Spyre
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