New · posted Oct 15
Centessa Pharmaceuticals (UK) · Pharmaceuticals
Director, External Quality Control & Stability
- Remote, US
- Remote
- Contract
- Director
Open until filled
The role
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026.
Description of Role
The Director, External Quality Control & Stability will provide leadership and oversight for analytical testing, stability programs, specification management, and quality control activities supporting clinical and commercial development.
The Director, External Quality Control & Stability role is a remote role based in the US.
What you need
- BS/MS/PhD in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field.
- 10+ years quality control and analytical development experience.
- Experience developing strategic vision as well as providing tactical support for quality control programs
What you'll do
Analytical Oversight and Tactical Support
- Develop and Lead analytical quality control strategy across multiple programs.
- Review analytical methods, specifications, and validation activities for adequacy and collaborate on updates, as required.
- Support analytical method transfer, as required
- Collaborate on supplier qualification and/or remediation activities.
Stability Program Leadership
- Oversee the stability program design and execution across multiple programs.
- Monitor and report on stability trends and product quality attributes as required.
- Ensure ongoing regulatory compliance of stability activities.
Supplier Oversight
- Manage supplier ongoing relationships.
- Perform routine reviews of testing results and overall quality of documentation.
- Drive issue resolution to facilitate regulatory compliance.
Regulatory Support
- Provide tactical support for regulatory submissions
- Support health authority inspections and audits, as required.
- Review analytical and stability sections within CMC filings.
Pay and benefits
$150,000 – $210,000 a year
Employer providedThe annual base salary range for this position is $150,000.00 to $210,000.00. Individual compensation within this range will be determined based on a variety of factors, including location, qualifications, skills, relevant experience, and job knowledge.
In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
Discretionary annual bonus
401(k) plan
Medical, dental, vision, and life insurance
Paid time off
Health and wellness program
From the posting
About Centessa Pharmaceuticals (UK)
Work Location
POSITION: Temporary, non-exempt
Equal opportunity, accessibility and legal noticesCentessa Pharmaceuticals (UK)'s statements, word for word
EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
Job intelligence
The context around this role
Live data · October 15, 2026
Salary intelligence
How the pay compares
This role's midpoint is 9% below the US median for Quality Control roles at this level.
This roleEmployer provided
Director roles in the US25 roles publishing pay
| Annual base pay | Low | Median | High |
|---|---|---|---|
| This role | $150,000 | — | $210,000 |
| All US (middle half) | $186,000 | $198,500 | $240,000 |
This role: Centessa Pharmaceuticals (UK)'s own published range. Comparisons: the base pay employers published on open Quality Control roles at the same level on Regulatory Jobs, October 15, 2026. Nothing is estimated.
Career trajectory
Where this role sits in Quality Control
The general path across 275 open Quality Control roles on Regulatory Jobs, with the titles they carry most. Not Centessa Pharmaceuticals (UK)'s own promotion track.
Skills DNA
What this role leans on
How many of the posting's 20 duty, requirement and summary lines touch each area. The posting's emphasis, not a proficiency score.
- Lab testing and methods12
- Collaboration and leadership5
- GMP and compliance3
- Validation and qualification3
- Documentation and SOPs2
- Regulatory submissions2
- Quality systems and risk2
- Investigations and CAPA1
Regulatory intelligence
The rules behind this role
Frameworks and standards this posting's work falls under, matched from its own words, each linked to the official source.
Company hiring pulse
Centessa Pharmaceuticals (UK) on Regulatory Jobs
- 6
- Open roles
- 6
- Distinct roles
- 2
- Locations
By discipline
- Regulatory3 50%
- Quality3 50%
By level
- Director5 83%
- Manager1 17%
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Director, External Quality Control & Stability at Centessa Pharmaceuticals (UK)
Open until filled. $150K–$210K a year, employer provided.